Essays about: "ribosome"

Showing result 1 - 5 of 11 essays containing the word ribosome.

  1. 1. Understanding the pathophysiology ofrecurrent UBTF mutations associated withpediatric AML

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Annie Paulsson; [2022]
    Keywords : Hematologi; Cancer; AML; UBTF; leukemi;

    Abstract : Acute myeloid leukaemia (AML) is highly heterogeneous haematological malignancy, which represents a challenge in the understanding of the disease. Relapse in AML is common, andmany relapsed patients respond poorly to conventional treatment, leading to a low survivalrate. READ MORE

  3. 2. 3′-end fluorescence labelling of long RNAs using terminal deoxynucleotidyl transferase

    University essay from Lunds universitet/Kemiska institutionen

    Author : Johannes Lidberg; [2022]
    Keywords : Physical biochemistry; Fluorescence; In vitro transcription; RNA; Terminal deoxynucleotidyl transferase; Nucleobase analogue; Chemistry;

    Abstract : Through recent years, RNA has rapidly gone from mainly being known as a passive information-carrying molecule within the central dogma of molecular biology to becoming the active ingredient in multiple therapeutics, such as in vaccines and potential drugs against cancer. However, one of the main challenges with RNA as a therapeutic is efficient delivery to cells. READ MORE

  4. 3. Characterization of the role of RbfA and KsgA in ribosome function

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Carina Kvernes Macpherson; [2022]
    Keywords : ;

    Abstract : Ribosome biogenesis is the maturation and accurate assembly of ribosomal RNA and proteins to form functional ribosomes competent to enter the translation cycle, facilitated by the action of ribosome biogenesis factors. RbfA and KsgA are two factors involved in late stages of the 30S subunit biogenesis, yet before translation initiation. READ MORE

  5. 4. Translation inhibition in Mycobacterium smegmatis by tuberactinomycins

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Wei Guo; [2022]
    Keywords : protein synthesis; tuberactinomycins; ribosome; tuberculosis; Mycobacterium smegmatis;

    Abstract : Tuberculosis continues to be a global health threat as multiple drug-resistant tuberculosis and extensively drug-resistant tuberculosis become increasingly rampant. Tuberactinomycins, specifically capreomycin, administered in combination with other medicines, remains one of the effective strategies against these deadly strains of tuberculosis. READ MORE

  6. 5. Fidelity of protein synthesis using sequence reconstructed ancient Elongation Factor Tu

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning; Uppsala universitet/Institutionen för cell- och molekylärbiologi

    Author : Hui Yu; [2021]
    Keywords : ;

    Abstract : To maintain a healthy growth rate of living cells, protein synthesis must take place accurately and efficiently. Translation, the core step decoding the genetic information, governs both fidelity and efficiency. READ MORE