Essays about: "rifampicin"

Showing result 1 - 5 of 8 essays containing the word rifampicin.

  1. 1. Evaluation of pretreatment methods for formalin-fixed paraffin-embedded extrapulmonary tuberculosis tissue : Improvement of lab developed molecular diagnostics of Mycobacterium-complex

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Anna-Sara Schultz; [2021]
    Keywords : ;

    Abstract : Tuberculosis (TB) disease is a world-wide spread disease caused by Mycobacterium tuberculosis which affects a significant percentage of the world population. The disease is often localized in the lungs, but can further develop and spread to other organs and is then called extrapulmonary TB (EPTB). READ MORE

  3. 2. Growth Dynamics, Antibiotic Susceptibility and the Effect of Sublethal Ciprofloxacin Concentrations in Susceptible and Resistant Escherichia coli in Biofilm

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Jenny Fernberg; [2019]
    Keywords : Biofilm; Escherichia coli; CFT073; BPC; MBIC; MSC; Ciprofloxacin; Streptomycin; Rifampicin; Antibiotic resistance; Urinary Tract Infections; Growth dynamics; Antibiotic susceptibility; S83F; K42N; S531L; Sub-MIC;

    Abstract : Instead of planktonic growth in nature, many species of bacteria form biofilm to survive in harsh conditions. Although many chronic bacterial infections are caused by bacterial species in a biofilm lifestyle, previous research has focused on studying antibiotic resistance in planktonic growth. Here we used a modified MBEC assay, i.e. READ MORE

  4. 3. Improving Antibiotic Availability by Restructuring the Supply Chain : A Case Study Within Sweden

    University essay from Uppsala universitet/Industriell teknik

    Author : Shailesh Garlapati; Vinana Sewoyo; [2019]
    Keywords : Pharmaceutical supply chain; Antibiotics; PLATINEA; Benzylpenicillin; Rifampicin; Antibiotic procurement; Antibiotics supply chain; Antimicrobial Resistance; AMR; Antibiotic Shortages;

    Abstract : Rising Antimicrobial Resistance is a threat faced all over the world. Bacterial infections that were treatable with antibiotics only a few years ago can now lead to life-threatening conditions. READ MORE

  5. 4. Screening for antibiotic combinationsagainst carbapenem-resistant Gram-negative bacteria

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Marcus Hong; [2018]
    Keywords : ;

    Abstract : Carbapenem-resistant Enterobacteriaceae is a growing problem. Not only are they resistant against carbapenems but the genes that encode for carbapenemase production, are often situated amongst other resistance genes making these bacteria resistant to multiple antibiotic classes. READ MORE

  6. 5. Individualization of fixed-dose combination regimens : Methodology and application to pediatric tuberculosis

    University essay from Uppsala universitet/Institutionen för farmaceutisk biovetenskap

    Author : Gunnar Yngman; [2015]
    Keywords : pharmacometrics; pharmacokinetics; PK; population pharmacokinetics; optimal design; FDC; fixed-dose combination; pediatrics; tuberculosis; rifampicin; pyrazinamide; isoniazid; ethambutol; modeling; simulation; estimation; allometric scaling; stochastical simulation and estimation; NONMEM; MATLAB; FO; FOCE; Expectation-Maximization algorithm; importance sampling; Nelder-Mead method; logistic function; discontinuity; euclidean distance; Sammon mapping; global minimum; local minima;

    Abstract : Introduction: No Fixed-Dose Combination (FDC) formulations currently exist for pediatric tuberculosis (TB) treatment. Earlier work implemented, in the software NONMEM, a rational method for optimizing design and individualization of pediatric anti-TB FDC formulations based on patient body weight, but issues with parameter estimation, dosage strata heterogeneity and representative pharmacokinetics remained. READ MORE