Essays about: "safety cases"

Showing result 1 - 5 of 316 essays containing the words safety cases.

1. 1. Quantification of Pharmaceuticals at the sub-cellular level using the NanoSIMS

   University essay from Uppsala universitet/Analytisk kemi

   Author : Maryam Dost; [2024]
   Keywords : Mass spectroscopy imaging; AstraZeneca; Nanosims; Therapeutics; pharmacokinetics; pharmacodynamics; Quantitative Visualization; calibration curve; RSF; pharmacology; Data Analysis; Chemistry; Quantification; isotopes; Pharmaceuticals; subcellular; drug; drug target; nucleotide; biodistribution; Bioanalytical electrochemistry; spectroscopy; mass spectrometry; analytical separations; Analytical Chemistry; ROI; Bioanalytical Chemistry; Masspektroskopi avbildning; AstraZeneca; Nanosims; Terapeutik; farmakokinetik; farmakodynamik; Kvantitativ visualisering; kalibreringskurva; RSF; farmakologi; Dataanalys; Kemi; Kvantifiering; isotoper; Läkemedel; subcellulär; läkemedel; läkemedelsmål; bioskopisk elektrofördelning; nukleotid; bioskopisk bioskopisk distribution; masspektrometri; analytiska separationer; analytisk kemi; bioanalytisk kemi;

   Abstract : Mass spectroscopy imaging (MSI) has become a vital tool in modern research due to its ability to visualize the spatial distribution of molecules within tissue samples. The collaboration between researchers at AZ, the University of Gothenburg, and Chalmers University of Technology using the NanoSIMS instrument and MSI-SIMS technology has opened up new avenues of exploration in pharmaceutical development, particularly in examining drugs and metabolites at sub-cellular levels. READ MORE

3. 2. Detecting inconsistencies of safety artifacts with Natural Language Processing Bachelor of Science Thesis

   University essay from Göteborgs universitet/Institutionen för data- och informationsteknik

   Author : Xuni Huang; [2023-01-09]
   Keywords : Inconsistencies; Safety-critical systems; Natural language processing; Classification;

   Abstract : This paper investigates a method that helps detect inconsistencies between safety-critical systems’ textual safety artifacts that safety cases rely on by involving NLP techniques. A design science research study was conducted in three iterations. I evaluate the method by conducting different experiments. READ MORE

4. 3. Uncertainty Estimation in Radiation Dose Prediction U-Net

   University essay from KTH/Skolan för elektroteknik och datavetenskap (EECS)

   Author : Frida Skarf; [2023]
   Keywords : Radiation dose prediction models; U-net; quantile regression; Monte Carlo Dropout; epistemic uncertainty estimation; aleatoric uncertainty estimation; Stråldospredicerande modeller; U-net; kvantilregression; Monte Carlo Dropout; epistemisk osäkerhetsskattning; aletorisk osäkerhetsskattning;

   Abstract : The ability to quantify uncertainties associated with neural network predictions is crucial when they are relied upon in decision-making processes, especially in safety-critical applications like radiation therapy. In this paper, a single-model estimator of both epistemic and aleatoric uncertainties in a regression 3D U-net used for radiation dose prediction is presented. READ MORE

5. 4. Lateral Control of Heavy Vehicles

   University essay from KTH/Väg- och spårfordon samt konceptuell fordonsdesign

   Author : Aravind Jawahar; Lokesh Palla; [2023]
   Keywords : Path Tracking; Collision Avoidance; Pure Pursuit; Stanley; Linear Quadratic Regulator; Sliding Mode Control; Model Predictive Control; Path Tracking; Collision Avoiding; Pure Pursuit; Stanley; Linear Quadratic Regulator; Sliding Mode Control; Model Predictive Control;

   Abstract : The automotive industry has been involved in making vehicles autonomous to different levels in the past decade rapidly. Particularly in the commercial vehicle market, there is a significant necessity to make trucks have a certain level of automation to help reduce dependence on human efforts to drive. READ MORE

6. 5. urStory : A Tool to Connect Generations Through Voice-Recorded Memories and Experiences

   University essay from Malmö universitet/Institutionen för konst, kultur och kommunikation (K3)

   Author : Ecenur Bacaksizlar; [2023]
   Keywords : Intergenerational Connections; Generational Gap; Digital Storytelling; Designing for Cultures; Interaction Design; Ageism;

   Abstract : Over the last decades, there has been a decline in the recognition and prevalence of communication and interaction between people of different age groups. This change can be perceived as a loss of value in societies on several different levels while this societal segregation continues to create larger divisions within societies. READ MORE