Essays about: "scfv"

Showing result 1 - 5 of 6 essays containing the word scfv.

1. 1. Formulation development of a recombinant VAR2-antiCD3 protein for cancer immunotherapy

   University essay from Lunds universitet/Livsmedelsteknik och nutrition (master)

   Author : Maja Warlin; Frida Hallberg; [2021]
   Keywords : immunotherapy; cancer; pharmaceuticals; proteins; analytical techniques; molecular biotechnology; formulation; life science; engineering; pharmaceutical technology; Technology and Engineering;

   Abstract : The use of immunotherapy for treating cancer has received a lot of attention in the recent years. The therapy is based on activating or deactivating the patient’s own immune system to help fight the disease. One way of doing this, is using bispecific molecules that can target both cancer cells and T-cells simultaneously. READ MORE

3. 2. Optimization of Calcium-Dependent Affinity Ligands for Protein Purification

   University essay from KTH/Proteinvetenskap

   Author : Linnea Öst; [2021]
   Keywords : Protein purification; Protein A; calcium-dependent; scFv; G-CSF; multimerization; mild elution; ZCa;

   Abstract : With an expanding life-science sector and growing production of recombinant proteins, the need for efficient downstream processing is increasing. Certain proteins are sensitive to the harsh conditions often used in protein purification, such as low pH, which can result in aggregation and denaturation. READ MORE

4. 3. IL13R⍺2-CAR T cells for Immunotherapy of Glioblastoma

   University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

   Author : Xu Zhu; [2021]
   Keywords : ;

   Abstract : Glioblastoma is the most malignant form of gliomas and is a highly infiltrative while non-metastatic tumor of the central nervous system. Patients with glioblastoma have a poor prognosis of 15 months median survival after diagnosis. READ MORE

5. 4. Calcium-dependent affinity ligands for protein purification

   University essay from KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

   Author : Emma Larsson; [2020]
   Keywords : Purification; Affinity chromatography; Protein A; Z domain; Calcium-dependent; ZCa; Elution;

   Abstract : The rapid growth of the biopharmaceutical industry has led to increasing demands on the protein production process. An important aspect is the yield of functional protein, which can be greatly affected by the choice of downstream purification. READ MORE

6. 5. Protein Stability, Folding and Design: Stabilization of scFv Protein through its reconstitution using a split GFB biosensor in vivo

   University essay from Lunds universitet/Kemiska institutionen

   Author : Kalyani Sanagavarapu; [2012]
   Keywords : Proteinvetenskap; Chemistry;

   Abstract : General rules for rational design as well as prediction of tertiary structure and functionality of a protein can be described by investigating the interactions and the role of particular amino acids in protein structure. Mutagenesis has been used commonly to generate stable variants, with an ultimate goal to unravel the rules of protein stability and folding. READ MORE