Essays about: "single chain variable fragment scFv"

Found 2 essays containing the words single chain variable fragment scFv.

1. 1. Optimization of Calcium-Dependent Affinity Ligands for Protein Purification

   University essay from KTH/Proteinvetenskap

   Author : Linnea Öst; [2021]
   Keywords : Protein purification; Protein A; calcium-dependent; scFv; G-CSF; multimerization; mild elution; ZCa;

   Abstract : With an expanding life-science sector and growing production of recombinant proteins, the need for efficient downstream processing is increasing. Certain proteins are sensitive to the harsh conditions often used in protein purification, such as low pH, which can result in aggregation and denaturation. READ MORE

3. 2. Development and characterization of Mantle Cell Lymphoma specific IgGs

   University essay from Institutionen för fysik, kemi och biologi

   Author : Katarina Gärdefors; [2008]
   Keywords : Mantle cell lymphoma MCL ; Sox11; human recombinant antibodies; single chain variable fragment scFv ; IgG.;

   Abstract : Mantle cell lymphoma (MCL) is one of several sub-types of B-cell lymphomas. The malignancy is very aggressive and average survival time is short. The hallmark of MCL is over expression of cyclin D1, however about 15% of all MCL cases do not display this over expression and are easily misdiagnosed. READ MORE