Essays about: "small molecular inhibitor"

Found 3 essays containing the words small molecular inhibitor.

1. 1. Cystatin C i urin som markör för akut njurskada hos hundar

   University essay from SLU/Dept. of Clinical Sciences

   Author : Sanna Isaksson; [2023]
   Keywords : cystatin C; AKI; hund; tubuliskada; urinmarkör;

   Abstract : Cystatin C är ett protein och en proteinasinhibitor med låg molekylärvikt (13kDa) som är involverat i intracellulär proteinkatabolism och produceras med konstant hastighet. Urin-cystatin C (uCysC) hos en frisk hund resorberas fullständigt i proximala tubuli och finns normalt i mycket små, ej mätbara mängder i urinen. READ MORE

3. 2. Investigation of endogenous p21 expression and its correlation to therapy resistance in high-risk neuroblastoma

   University essay from KTH/Proteinvetenskap

   Author : Agnes Sorteberg; [2021]
   Keywords : p21; high-risk neuroblastoma; small molecular inhibitor; chemo-resistance; combination treatment;

   Abstract : Neuroblastoma (NB) is a childhood cancer with a highly complex nature. High-risk NB patients undergo intensive treatment regimens that are often followed by long-term side effects. This, in addition to the emergence of resistant cancer cells, highlights a need for novel therapeutic targets and treatment strategies to improve outcome in NB. READ MORE

4. 3. Genetic heterogeneity of EGFR and KRAS mutations in primary tumor tissue from non-small cell lung cancer patients

   University essay from Institutionen för medicinsk biokemi och mikrobiologi

   Author : Johanna Mattsson; [2011]
   Keywords : Non-small cell lung cancer; KRAS; EGFR; heterogeneity; mutation;

   Abstract : Activated epidermal growth factor receptor (EGFR) and Kirsten rat sarcoma viral oncogene homolog (KRAS) mutations characterize molecular subgroups of non-small cell lung cancer (NSCLC) and have a strong predictive value for response to EGFR inhibitor therapy. Recently, EGFR mutation testing was included in the diagnostic algorithm of NSCLC. READ MORE