Essays about: "spectroscopy drugs"

Showing result 1 - 5 of 17 essays containing the words spectroscopy drugs.

1. 1. Quantification of Pharmaceuticals at the sub-cellular level using the NanoSIMS

   University essay from Uppsala universitet/Analytisk kemi

   Author : Maryam Dost; [2024]
   Keywords : Mass spectroscopy imaging; AstraZeneca; Nanosims; Therapeutics; pharmacokinetics; pharmacodynamics; Quantitative Visualization; calibration curve; RSF; pharmacology; Data Analysis; Chemistry; Quantification; isotopes; Pharmaceuticals; subcellular; drug; drug target; nucleotide; biodistribution; Bioanalytical electrochemistry; spectroscopy; mass spectrometry; analytical separations; Analytical Chemistry; ROI; Bioanalytical Chemistry; Masspektroskopi avbildning; AstraZeneca; Nanosims; Terapeutik; farmakokinetik; farmakodynamik; Kvantitativ visualisering; kalibreringskurva; RSF; farmakologi; Dataanalys; Kemi; Kvantifiering; isotoper; Läkemedel; subcellulär; läkemedel; läkemedelsmål; bioskopisk elektrofördelning; nukleotid; bioskopisk bioskopisk distribution; masspektrometri; analytiska separationer; analytisk kemi; bioanalytisk kemi;

   Abstract : Mass spectroscopy imaging (MSI) has become a vital tool in modern research due to its ability to visualize the spatial distribution of molecules within tissue samples. The collaboration between researchers at AZ, the University of Gothenburg, and Chalmers University of Technology using the NanoSIMS instrument and MSI-SIMS technology has opened up new avenues of exploration in pharmaceutical development, particularly in examining drugs and metabolites at sub-cellular levels. READ MORE

3. 2. Development of a PNA-drug conjugate for pretargeted delivery of cytotoxic drugs

   University essay from Uppsala universitet/Theranostics

   Author : Astrid Haraldsson; [2023]
   Keywords : PNA; pretargeting; cancer therapy; cytotoxic payload;

   Abstract : One of the major challenges in cancer treatment is delivering high enough doses of active substance specifically to cancer cells without accumulation in healthy organs. Pretargeting has emerged as a potential solution, where the delivery of a cancer recognizing (primary) agent and a cancer killing (secondary) agent are separated. READ MORE

4. 3. Coacervates as a subcutaneous drug delivery system

   University essay from Uppsala universitet/Institutionen för läkemedelskemi

   Author : Dania Elkhalifa; [2022]
   Keywords : ;

   Abstract : Subcutaneous administration of biological drugs has become highly attractive as it offers the possibility for patient self-administration. Coacervates as a subcutaneous drug delivery system provide a way to decrease injection volumes thereby reducing the risk of injection site pain. READ MORE

5. 4. 3′-end fluorescence labelling of long RNAs using terminal deoxynucleotidyl transferase

   University essay from Lunds universitet/Kemiska institutionen

   Author : Johannes Lidberg; [2022]
   Keywords : Physical biochemistry; Fluorescence; In vitro transcription; RNA; Terminal deoxynucleotidyl transferase; Nucleobase analogue; Chemistry;

   Abstract : Through recent years, RNA has rapidly gone from mainly being known as a passive information-carrying molecule within the central dogma of molecular biology to becoming the active ingredient in multiple therapeutics, such as in vaccines and potential drugs against cancer. However, one of the main challenges with RNA as a therapeutic is efficient delivery to cells. READ MORE

6. 5. Simulation of THz Quantum Cascade Lasers

   University essay from Lunds universitet/Matematisk fysik; Lunds universitet/Fysiska institutionen

   Author : Viktor Rindert; [2021]
   Keywords : Physics and Astronomy;

   Abstract : Quantum Cascade Lasers (QCLs) have since their invention in 1994 become a crucial source for mid-infrared and THz radiation. Mid-infrared QCLs have achieved room temperature operation while THz QCLs have not. As such, simulations are an important tool in order to achieve a THz QCL operational at room temperature. READ MORE