Essays about: "stroma"

Showing result 1 - 5 of 16 essays containing the word stroma.

  1. 1. Assessment and evaluation of heterogeneity in data from immune infiltration spatial niches in lung cancer

    University essay from Lunds universitet/Matematisk statistik

    Author : Mahta Keivani Najafabadi; [2023]
    Keywords : Mathematics and Statistics;

    Abstract : The protein biomarker expressions in three types of sampled immune INFILTration spatial niches in lung cancer tissue were measured using the new technology Digital Spatial Profiler (DSP). The three types of immune INFILTration that were observed in lung tumors were STROMA identified as immune cells separate from tumor cells, Tertiary lymphoid structures (TLS) identified as dense structures of organized immune cells and finally Infiltraterate where immune cells dispersed among and in direct contact with tumor cells (INFILT). READ MORE

  3. 2. Potency Analysis of Mesenchymal Stromal Cells Towards Innate and Adaptive Immune Cells

    University essay from KTH/Proteinvetenskap

    Author : Linn Garbers; [2023]
    Keywords : Mesenchymal stroma cells; T cells; interferon gamma; cytokines; tumor necrosis factor alpha; mesenkymala stromaceller; T-celler; interferon gamma; cytokiner; tumörnekrosfaktor alpha;

    Abstract : Studien utvärderar egenskaper hos mesenkymala stromaceller (MSC) i passage 2 och 3. I ett samarbete mellan Cellcolabs och Karolinska Institutet (KI) genomfördes projektet med Katarina Le Blancs forskargrupp. READ MORE

  4. 3. The Effect of Angiogenesis Inhibition on Tumor-Associated Granulocytes in an Orthotopic Model of High-Risk Neuroblastoma

    University essay from Uppsala universitet/Institutionen för farmaceutisk biovetenskap

    Author : Maja Hammarström; [2022]
    Keywords : neuroblastoma; tumor angiogenesis; sunitinib; SU11248; tumor-associated neutrophils; immunohistochemistry;

    Abstract : Background: Neuroblastoma is the most common extracranial solid tumor in children. The survival rate in high-risk neuroblastoma is less than 50 % despite intensive multimodal therapy, and there is thus an immense need for new treatment options. READ MORE

  5. 4. Knockout studies of Panc1 cells

    University essay from KTH/Tillämpad fysik

    Author : Martin Sundin; [2021]
    Keywords : PDAC; crosstalk; stroma; spheroid; western blot; viability; gemcitabine.; PDAC;  verh rning; stroma; sf roid; western blot; viabilitet; gemcitabine.;

    Abstract : Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal form of cancerwith very few available treatment options of which none has great effect.Cancer cells and stromal cells such as stellate cells which exist in abundancein PDAC interact by crosstalk, resulting in a tumorigenic collective response. READ MORE

  6. 5. The effect of deactivation or silencing of tumor stroma with angiogenesis inhibitor on malignancy of tumor metastases

    University essay from Uppsala universitet/Institutionen för farmaceutisk biovetenskap

    Author : Nataly Tachijian; [2021]
    Keywords : neuroblastoma; SU11248; angiogenesis; tumor-associated macrophages; immunohistochemistry;

    Abstract : Background: Neuroblastoma (NB) is a pediatric tumor in infants and young children. The survival rate is only around 50 percent for high-risk NB despite advanced and intense multi-modal therapy. Current research aims to find new effective treatment additional to modern therapy to improve prognosis of high-risk NB in children. READ MORE