Essays about: "structural conformation"

Showing result 1 - 5 of 10 essays containing the words structural conformation.

  1. 1. Evaluating a coarse-grained IDP-model for structure and dynamics

    University essay from Lunds universitet/Biofysikalisk kemi

    Author : Louise Kalander; [2021]
    Keywords : IDP; Intrinsically disordered proteins; Histatin 5; Simulation; Biophysical chemistry; Chemistry;

    Abstract : In this study a coarse-grained model of intrinsically disordered proteins (IDPs) is evaluated to determine whether the model is suitable to use for analyzing the structure and dynamics of IDPs. IDPs are proteins that lack a stable tertiary structure which gives them a flexible structure. READ MORE

  3. 2. Structural basis of modulation by pH and calcium in a ligand-gated ion channel

    University essay from KTH/Genteknologi

    Author : Olivia Andén; [2021]
    Keywords : Pentameric ligand-gated ion channels; bacterial homolog; protein expression; protein purification; cryo-electron microscopy; data processing; protein structure; Pentamerisk ligandstyrd jonkanal; bakteriell homolog; proteinexpression; proteinrening; kryo-elektronmikroskopi;

    Abstract : Pentameriska ligandstyrda jonkanaler (pLGICs) är avgörande för omvandlingen av kemisk till elektrisk signalöverföring i djurs nervsystem. Dysfunktion i dessa kanaler har visat sig vara kopplad till flera sjukdomar inklusive epilepsi, schizofreni, Alzheimers och autism, vilket gör dem till en måltavla för en mängd olika läkemedel. READ MORE

  4. 3. Clustering approaches for extracting structural determinants of enzyme active sites

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Ismini - Christina Stamatelou; [2020]
    Keywords : Structural bioinformatics; enzyme; active site; glycogen phosphorylase; clustering; rotamer; conformation; k-means; clara;

    Abstract : The study of enzyme binding sites is an essential but rather demanding process of increased complexity since the amino acids lining these areas are not rigid. At the same time, the minimization of side effects and the specificity of new ligands is a great challenge in the structure-based drug design approach. READ MORE

  5. 4. Determination of specificity and affinity of the Lactose permease (LacY) protein of Escherichia coli through application of molecular dynamics simulation

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Stuart Lutimba; [2018]
    Keywords : ;

    Abstract : Proteins are essential in all living organisms. They are involved in various critical activities and are also structural components of cells and tissues. READ MORE

  6. 5. Hovsprickor hos häst

    University essay from SLU/Dept. of Clinical Sciences

    Author : Ida Josefin Jormhed; [2016]
    Keywords : hovsprickor; häst; hoof cracks; horse;

    Abstract : Hovkapseln är hovens epidermis och den omsluter, skyddar och stödjer kötthoven som utgörs av hovens inre strukturer. Hovkapseln har till uppgift att bära vikt, tåla nötning samt utgöra halkskydd och genom sin formbarhet möjliggör den sänkning av belastningsamplituder. READ MORE