Essays about: "total oxidizable precursor TOP assay"
Showing result 1 - 5 of 6 essays containing the words total oxidizable precursor TOP assay.
-
1. Do selected CF3-containing pharmaceuticals oxidize to trifluoroacetic acid (TFA)? – Analysis of ultra-short perfluoroalkyl acids (PFAAs) and their analytical challenges following oxidation
University essay from Örebro universitet/Institutionen för naturvetenskap och teknikAbstract : Total oxidizable precursor assay (TOPA) has been used to understand the contribution of unknown precursors to the extractable organofluorine (EOF) compounds. The investigation of compounds containing a CF3 moiety especially connected to an aromatic ring is important because any compounds with such a moiety (pharmaceuticals) may oxidize to form trifluoroacetic acid (TFA). READ MORE
-
2. Could fluorinated pharmaceuticals have an impact on the EOF amount in human blood?
University essay from Örebro universitet/Institutionen för naturvetenskap och teknikAbstract : Recent studies have discovered an increasing amount of unknown organofluorine in human blood. This increase insinuate that humans might be exposed to potentially new and unidentified organofluorine compounds. READ MORE
-
3. Total oxidizable precursor assay: Applications and limitations. A study on the occurrence of perfluoroalkyl and polyfluoroalkyl substances (PFASs) in Chinese Wastewater Treatment Plants
University essay from Örebro universitet/Institutionen för naturvetenskap och teknikAbstract : Total oxidizable precursor (TOP) assay is an in-lab method which oxidatively converts precursor compounds of poly- and perfluoroalkyl substances (PFASs) into measurable perfluorinated alkyl acids (PFAAs). The method is a very strong tool to semi-quantify PFASs that would otherwise be missed in conventional targeted analysis using liquid chromatography - tandem mass spectrometry (LC-MS/MS). READ MORE
-
4. The study of organofluorine analysis applied to totaloxidizable precursor (TOP) assay to understand perandpolyfluoroalkyl substances (PFASs)
University essay from Örebro universitet/Institutionen för naturvetenskap och teknikAbstract : Per- and polyfluoroalkyl substances (PFASs) are synthetic chemicals which are used in a wide range of applications such as aqueous film forming foam (AFFF) for firefighting, paint, coating and cosmetics. For almost a decade, PFASs have received worldwide attention because of the ubiquitous detection of PFAS in the environment and their bioaccumulative, persistent and give toxic effects on animals and humans. READ MORE
-
5. A study to understand the information gap between total organofluorine analysis and total oxidizable precursor assay on polyfluoroalkyl/perfluoroalkyl substances (PFASs)
University essay from Örebro universitet/Institutionen för naturvetenskap och teknikAbstract : Total oxidizable precursor (TOP) assay is an oxidation method to convert precursor compound of polyfluoroalkyl/perfluoroalkyl substances (PFASs) into measurable perfluorinated carboxylic acids (PFCAs). A previous mass balance study has shown that a loss of fluorine was observed after employing the method to convert the precursors in firefighting foams. READ MORE
