Essays about: "transcription factor binding motifs"

Found 4 essays containing the words transcription factor binding motifs.

  1. 1. Identification of de novo Transcription Factor Binding Motifs Created by Cancer-related Mutations

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Siqi Li; [2022]
    Keywords : transcription factor binding motifs; funMotifs; PCAWG; mutations; de novo motifs;

    Abstract : In many countries, cancer is one of the biggest threats for citizens’ health, especially among aged people. Genomic mutations play a crucial role in cancer cell development. In previous decades, cancer research has been mainly focused on mutations in coding regions. READ MORE

  3. 2. The role of RFX-target genes in neurodevelopmental and psychiatric disorders

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Abhishekapriya Ganesan; [2021]
    Keywords : ;

    Abstract : Neurodevelopmental disorders such as autism spectrum disorder (ASD) and psychiatric disorders, for example, schizophrenia (SCZ) represent a large spectrum of disorders that manifest through cognitive and behavioural problems. ASD and SCZ are both highly heritable, and some phenotypic similarities between ASD and SCZ have sparked an interest in understanding their genetic commonalities. READ MORE

  4. 3. Characterisation of Transcription Factor Regulation During the Development of Zebrafish Craniofacial Structures

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Jake Leyhr; [2018]
    Keywords : ;

    Abstract : The appearance of jaws approximately 420 million years ago was a major event in vertebrate evolution. This new structure allowed gnathostomes to take on roles as active predators and increase their energy intake, facilitating their success as a group. READ MORE

  5. 4. A Peak-Finder Meta Server for ChIP-Seq Analysis

    University essay from Institutionen för informationsteknologi

    Author : Husen Umer; [2011]
    Keywords : ;

    Abstract : Chromatin immunoprecipitation (ChIP) coupled with ultra high-throughput parallel sequencing (ChIP-seq) is widely used to study transcriptional regulation on a genome wide scale. Numerous computational tools have been developed to identify transcription factor (protein) binding sites from large ChIP-seq datasets. READ MORE