Essays about: "tumour necrosis factor"

Showing result 1 - 5 of 6 essays containing the words tumour necrosis factor.

  1. 1. Testing Coagulation Potential of Extracellular Vesicles Derived from Aortic Stenosis Patients on Human Cardiac Spheroids

    University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Author : Muhammad Nafiz Ikhwan Bin Nor Fuad; [2023]
    Keywords : Extracellular vesicles; human aortic endothelial cells; tissue factor; TNFα; coagulation pathway; cardiac spheroids;

    Abstract : Cardiovascular diseases have always been the leading cause of global morbidity and mortality. Aortic stenosis, which is a kind of cardiovascular disease has a high prevalence in elderlies that are 75 years and older. Currently, the only available treatment would be valve replacement surgery. READ MORE

  3. 2. IL-17A induced response and synergy with otherproinflammatory cytokines in human endothelial cells

    University essay from Örebro universitet/Institutionen för naturvetenskap och teknik

    Author : Julia Salin; [2021]
    Keywords : cDNA; complementary DNA CVD; cardiovascular disease CXCL1; C-X-C motif ligand-1 EC; endothelial cell ELISA; Enzyme-Linked Immunosorbent Assay HUVECs; human umbilical cord endothelial cells sIL-6R; soluble interleukin 6 receptor IL; interleukin NF-𝜅B; nuclear factor 𝜅B qPCR; quantitative polymerase chain reaction TNF; tumour necrosis factor VSMC; vascular smooth muscle cell;

    Abstract : Cardiovascular diseases are a broad group of diseases, such as heart attack and heart failureaffecting the cardiovascular system. The primary cause of cardiovascular diseases isatherosclerosis, and its progression is brought about by oxidative stress and a complex chronicinflammation reaction cascade. READ MORE

  4. 3. Efficacy of Methotrexate in the Treatment of Psoriatic Arthritis: A Critical Literature Review

    University essay from Lunds universitet/Läkarutbildningen

    Author : Christoffer Lindbom; [2019]
    Keywords : psoriatic arthritis; methotrexate; tumour necrosis factor inhibitor; efficacy; Medicine and Health Sciences;

    Abstract : Background: Psoriatic arthritis (PsA) is an inflammatory joint disease occurring in up to 30% of psoriasis patients. Relatively few clinical trials assess PsA treatment and data presentation in these are far from uniform making comparisons difficult. Objectives: To perform a literature review on methotrexate (MTX) efficacy in PsA. READ MORE

  5. 4. High mobility group box protein-1 (HMGB-1) vid osteoartrit hos häst

    University essay from SLU/Dept. of Biomedical Sciences and Veterinary Public Health

    Author : Tobias Wrangberg; [2014]
    Keywords : häst; osteoartrit ; inflammation; biomarkörer; cytokiner; HMGB-1; equine; osteoarthritis ; inflammation; biomarkers; cytokines;

    Abstract : Osteoartrit (OA) är den vanligaste orsaken till för tidig pension av tävlingshästar och är den sjukdom som står för den enskilt största ekonomiska förlusten inom hästnäringen. Diagnostiken är svår i ett tidigt skede vilket gör att man vill hitta bra markörer och inflammationsmediatorer som kan användas för att snabbt ställa rätt diagnos samt sätta in lämplig behandling. READ MORE

  6. 5. Kan kombinationen av dehydrering, kronisk stress och/eller endotoxemi vara orsaken till träningsinducerad lungblödning?

    University essay from SLU/Dept. of Anatomy, Physiology and Biochemistry

    Author : Petra Lernö; [2011]
    Keywords : träningsinducerad lungblödning; endotoxinemi; endotoxemi; LPS; dehydrering; stress; saltbrist;

    Abstract : Thoroughbred racehorses have suffered from exercise-induced haemorrhage for over 300 years. Almost all competing horses develop exercise-induced pulmonary haemorrhage (EIPH) at some point but most horses don’t suffer from reduced competing capacity due to the disease. The cause of the exercise-induced haemorrhage is unknown. READ MORE