Essays about: "zinc finger"
Showing result 1 - 5 of 6 essays containing the words zinc finger.
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1. Identification of de novo Transcription Factor Binding Motifs Created by Cancer-related Mutations
University essay from Uppsala universitet/Institutionen för biologisk grundutbildningAbstract : In many countries, cancer is one of the biggest threats for citizens’ health, especially among aged people. Genomic mutations play a crucial role in cancer cell development. In previous decades, cancer research has been mainly focused on mutations in coding regions. READ MORE
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2. Generation of induced pluripotent stem cells (iPSCs) lines deficient for genes associated with neurodevelopmental diseases using CRISPR/Cas9 technology
University essay from Uppsala universitet/Institutionen för biologisk grundutbildningAbstract : Induced pluripotent stem cells (iPSCs) can self-renew and differentiate into many other cell types. IPSCs are derived from somatic cells, and upon reprogramming, they share an expression profile similar to embryonic stem cells (ESCs). READ MORE
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3. Exploration of Zinc finger CCCH domain-containing protein 11A’s role in mammalian cell NFkB Pathway
University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologiAbstract : ZC3H11A (ZC3) protein has been reported to be part of the TREX (TRanscription-EXport) nuclear export system for mammalian cells. According to our previous publication, ZC3 not only plays an unelucidated role in the TREX complex, but also supports the growth of several human nucleus replicating virus, such as influenza virus, adenovirus (HAdV), herpes simplex virus and HIV. READ MORE
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4. Characterization of DNA binding of the two zinc finger domains of transcription factor zBED6
University essay from Uppsala universitet/Institutionen för biologisk grundutbildningAbstract : The zinc finger protein, zBED6, is a transcriptional regulator of IGF2 along with hundreds of other genes relating to development and growth. Studies on the growth of commercially bred pigs discovered a single nucleotide substitution in the third intron of IGF2 which disrupts the binding of zBED6 and is responsible for the three-fold upregulation of IGF2 in skeletal muscle. READ MORE
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5. Xenotransplantation : nya möjligheter
University essay from SLU/Dept. of Biomedical Sciences and Veterinary Public HealthAbstract : Transplantation innebär att ett organ eller vävnad tas från en individ och ges till en annan individ med behov av organet eller vävnaden. Ett problem globalt är att det finns för få tillgängliga organ för transplantation. READ MORE