Oral fluoride retention after use of mouth rinses with different fluoride content.

Abstract: Abstract Objective: The purpose of the study is to investigate how fluoride content in saliva depends on different fluoride mouth rinses: 1450 ppm, 910 ppm, 225 ppm and to compare a new 1450 ppm fluoride mouth rinse with the other concentrations. Material and method: The study included 17 subjects which rinsed with three different mouth rinses, A (225 ppm), B (1450 ppm) and C (910 ppm) at three different times. They rinsed for 1 minute and then spat out all content in a container. After different intervals they passively transferred their saliva into a given container for 1 minute. The samples were sealed and stored in a freezer until the time of analyzing. After the trial, the samples were taken out of the freezer and were reheated. They were mixed with TISAB III and measured with an ion specific electrode. The group’s values were compared by analyzing the results using Tukey’s test. Results: A visible difference between the three mouth rinses were detected, however, only the difference between mouth rinse A and B were deemed statistically significant at all time points. A statistical significant difference between mouth rinse B and C were found at the time point of 45 minutes. Conclusion: There is a statistical significant difference between the new, high fluoride containing mouth rinse B and mouth rinse A, but there is not enough data in the study to see a statistically significant difference between mouth rinse B and C, or A and C. Further studies need to be made.