Essays about: "Germline genome editing"

Found 3 essays containing the words Germline genome editing.

  1. 1. CRISPR AND THETREATMENT/EN DISTINCTION : On Vagueness, Borderline Cases and Germline Genome Editing

    University essay from Umeå universitet/Institutionen för idé- och samhällsstudier

    Author : Ellen Svensson; [2021]
    Keywords : CRISPR; Treatment; Enhancement; Vagueness; Borderline cases; Slippery slope; Germline genome editing; GGE; Gene editing; Distinction; Ethics; Radical Enhancement; Human Nature; Eugenics;

    Abstract : In this thesis, I argue that the treatment/enhancement distinction that is central to the ethical debate concerning germline genome editing and CRISPR is too vague to be ethically and normatively guiding. The problem of vagueness is twofold, being both a semantic and epistemic issue. READ MORE

  3. 2. Preimplantation genetic diagnosis and therapy in humans- Opportunities and risks

    University essay from Örebro universitet/Institutionen för medicinska vetenskaper

    Author : Rickard Hedberg; [2020]
    Keywords : Preimplantation genetic diagnosis; CRISPR-Cas systems; gene editing; germline; genome; ethics; autonomy; beneficence; risks.;

    Abstract : IntroductionPreimplantation Genetic Diagnosis (PGD) was developed in the 1990s and has been used since to diagnose and discard embryos with genetic conditions or chromosomal abnormalities. CRISPR-Cas9 was discovered in 2012 and has been used in research, but has not become clinical practice on humans yet. READ MORE

  4. 3. Generating large-scale conditional knock-in mouse models using CRISPR/Cas9 in embryonic stem

    University essay from SLU/Dept. of Animal Breeding and Genetics

    Author : Gus Rowan Mcfarlane; [2016]
    Keywords : CRISPR Cas9; conditional knock-in mice; transgenic mice; Fbxw7; colorectal cancer;

    Abstract : The discovery and repurposing of CRISPR/Cas9 has revolutionized the field of genome editing and allowed for the development of mouse models with unprecedented simplicity and speed. The application of CRISPR/Cas9 in mouse embryonic stem cells represents a highly efficient and wellestablished method for generating large-scale conditional knock-in mouse models. READ MORE