Essays about: "RNA-binding"

Showing result 6 - 10 of 11 essays containing the word RNA-binding.

1. 6. Expression of FLAG-tagged argonautes in Dictyostelium discoideum

   University essay from Uppsala universitet/Institutionen för biologisk grundutbildning; Uppsala universitet/Institutionen för cell- och molekylärbiologi

   Author : Zozek Abdul Rahman; [2022]
   Keywords : Dictyostelium; discoideum; Argonaute; Protein; FLAG; FLAG-tag; Molecular Biology; Microbiology; SorMC; agnA; agnC; agnE; electrophoresis; pDM304;

   Abstract : Argonautes are conserved RNA-binding proteins that can regulate gene expression post transcriptionally through a process known as RNA interference (RNAi). This is done through the use of small RNAs, e.g. sRNAs that act as a guide for the argonautes, allowing for sequence-specific binding to the target site. READ MORE

3. 7. Social Behavior in a Zebrafish Model of Schizophrenia

   University essay from KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

   Author : Dagmar Halldorsdottir; [2022]
   Keywords : Zebrafish; Schizophrenia; RNA binding motif protein 12 gene RBM12 ; Personal space; Average inter-fish distance; Anxiety-like behavior; Wall-hugging; Speed; Bottom-dwelling;

   Abstract : Schizophrenia is a severe psychiatric disorder with unsatisfactory treatment options and poorly under- stood etiology. Genetic models are a suitable tool for studying this disorder with its high heritability. However, currently available animal models do not cover the broad range of schizophrenia symptoms and are not disorder-specific. READ MORE

4. 8. Analysis of the relation between RNA and RBPs using machine learning

   University essay from Linnéuniversitetet/Institutionen för datavetenskap och medieteknik (DM)

   Author : Mattias Wassbjer; [2021]
   Keywords : Machine Learning; Supervised Learning; Linear Regression; RNA-binding Proteins; LIME; T-Cells; CD4 Cells; K-mer; Bag of Words; RBP Activity Prediction;

   Abstract : The study of RNA-binding proteins has recently increased in importance due to discoveries of their larger role in cellular processes. One study currently conducted at Umeå University involves constructing a model that will be able to improve our knowledge about T-cells by explaining how these cells work in different diseases. READ MORE

5. 9. Integration of microfluidic sample handlingwith ultra-sensitive magnetic bioassay usinghigh-Tc Superconducting Quantum InterferenceDevice readout

   University essay from Uppsala universitet/Nanoteknologi och funktionella material

   Author : Emil Eriksson; [2016]
   Keywords : ;

   Abstract : Immunoassays are a very sensitive molecular diagnostics technique that uses biochemical reactions to measure concentration of biomolecules in a solution. ELISA is one of the most commonly used type, based on fluorescence, in routine medicaldiagnostics. It is time consuming and requires relatively large sample volumes. READ MORE

6. 10. Statistical Analysis of PAR-CLIP data

   University essay from KTH/Beräkningsbiologi, CB

   Author : Monica Golumbeanu; [2013]
   Keywords : statistical modeling; PAR-CLIP; RNA-binding proteins; Bayesian analysis;

   Abstract : From creation to its degradation, the RNA molecule is the action field of many binding proteins with different roles in regulation and RNA metabolism. Since these proteins are involved in a large number of processes, a variety of diseases are related to abnormalities occurring within the binding mechanisms. READ MORE