Essays about: "Biomarker discovery"

Showing result 1 - 5 of 12 essays containing the words Biomarker discovery.

  1. 1. Profiling the Blood Proteome in Autoimmune Disease Using Proximity Extension Assay

    University essay from KTH/Proteinvetenskap

    Author : Julia Asp; [2023]
    Keywords : Plasma proteomics; proximity extension assay; autoimmune disease; differential expression; machine learning; biomarkers; Plasma proteomik; proximity extension assay; autoimmuna sjukdomar; differentiellt proteinuttryck; maskininlärning; biomarkörer;

    Abstract : Autoimmuna sjukdomar är en samling komplexa, kroniska, inflammatoriska sjukdomstillstånd som kännetecknas av dysreglering av immunsystemet, vilket resulterar i inflammation och skada av vävnader, celler och organ. Dessa sjukdomar har en betydande inverkan på individens livskvalitet och bidrar ofta till ökad dödsrisk där komorbiditeter föreligger. READ MORE

  3. 2. Comparison and optimization of extracellular vesicle (EV) capturing on functional thin films for their molecular profiling

    University essay from KTH/Tillämpad fysik

    Author : Prattakorn Metem; [2023]
    Keywords : extracellular vesicle; plasmonic nanohole array; atomic force microscopy; fluorescence analysis; extracellulära vesiklar; nanohålsuppsättning; atomkraftsmikroskopi; fluorescensanalys;

    Abstract : Extracellular vesicles (EVs) are lipid bilayer encapsulated nanoparticles which have emerged as an excellent source of biomarkers for multiple diseases, including cancer. However, they are highly heterogeneous in their molecular compositions which remains a major challenge hindering the utilization of their biomarker potential. READ MORE

  4. 3. ATLAS DATABASES OF HUMAN BRAIN ANATOMY: QUALITATIVE AND QUANTITATIVE COMPARISON

    University essay from

    Author : Amanda Philipsson Franzén; [2021-01-11]
    Keywords : Medical physics; Brain atlas concordance problem; Quantitative comparison; Qualitative comparison; Hammersmith; 2012 MICCAI Multi-Atlas Labelling Challenge Data;

    Abstract : The purpose of this study was to quantitatively and qualitatively compare the two brain atlases databases, Hammersmith and 2012 MICCAI Multi-Atlas Labelling Challenge data, by developing a quantitative method. Theory Anatomical atlases of the human brain provide reference information about its structure. READ MORE

  5. 4. Profiling the autoantibody repertoire in systemic sclerosis

    University essay from KTH/Proteinvetenskap

    Author : Emmie Pohjanen; [2021]
    Keywords : Systemic sclerosis; rheumatology; autoimmunity; autoantibody; biomarkers; Systemisk skleros; reumatologi; autoimmunitet; autoantikropp; biomarkörer;

    Abstract : Systemisk skleros (SSc) är en autoimmun rheumatisk sjukdom som kännetecknas av fibros i huden och/eller de interna organen, vaskulopati och en autoimmun reaktion från immunförsvaret, med eller utan specifika autoantikroppsprofiler. Diagnostisering och sjukdomsbehandling försvåras av sjukdomens heterogena natur. READ MORE

  6. 5. Sepsis and circulating miRNA : The road towards absolute quantification of unknown miRNA levels in plasma utilizing two-tailed RT-qPCR, while testing two extraction methods, striving to create multi-marker panel for sepsis diagnosis

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Hazzim Elawad; [2021]
    Keywords : ;

    Abstract : Sepsis is a preventable yet life threatening condition, resulting from body response to infection. Time is crucial in sepsis diagnosis since deterioration in patients’ health can occur rapidly. Blood culturing is the gold standard for diagnosis, along with clinical assessment. READ MORE