Essays about: "Plasma proteomics"

Showing result 1 - 5 of 8 essays containing the words Plasma proteomics.

  1. 1. Profiling the Blood Proteome in Autoimmune Disease Using Proximity Extension Assay

    University essay from KTH/Proteinvetenskap

    Author : Julia Asp; [2023]
    Keywords : Plasma proteomics; proximity extension assay; autoimmune disease; differential expression; machine learning; biomarkers; Plasma proteomik; proximity extension assay; autoimmuna sjukdomar; differentiellt proteinuttryck; maskininlärning; biomarkörer;

    Abstract : Autoimmuna sjukdomar är en samling komplexa, kroniska, inflammatoriska sjukdomstillstånd som kännetecknas av dysreglering av immunsystemet, vilket resulterar i inflammation och skada av vävnader, celler och organ. Dessa sjukdomar har en betydande inverkan på individens livskvalitet och bidrar ofta till ökad dödsrisk där komorbiditeter föreligger. READ MORE

  3. 2. Exploring IGF interactions in the context of amyotrophic lateral sclerosis

    University essay from KTH/Proteinvetenskap

    Author : Axelina Schmidt; [2023]
    Keywords : cerebrospinal fluid; plasma; insulin-like growth factors IGFs ; amyotrophic lateral sclerosis; affinity proteomics; cerebrospinalvätska; plasma; insulinliknande tillväxtfaktorer IGF ; amyotrofisk lateralskleros; affinitetsproteomik;

    Abstract : Amyotrofisk lateral skleros (ALS) är en progressiv och dödlig neurodegenerativ sjukdom som påverkar motorneuroner i både hjärnan och ryggraden. Dagens ALS forskning har ett fokus på att skapa en bättre förståelse för både sjukdomsmekanism och de metaboliska processer som bidrar till sjukdomen. READ MORE

  4. 3. Biologically informed neural network for subphenotype classification in septic AKI

    University essay from Lunds universitet/Avdelningen för Biomedicinsk teknik

    Author : Erik Hartman; [2022]
    Keywords : Machine learning; neural networks; proteomics; sepsis; AKI; Technology and Engineering;

    Abstract : Sepsis is a life threatening condition where the body’s reaction to an infection results in a dysregulated immune response - ultimately causing damage to tissues and organs. The syndrome is diverse, both in underlying biology, disease manifestation and severity, and is therefore divided into endotypes and further into subphenotypes. READ MORE

  5. 4. A pipeline for the identification and examination of proteins implicated in frontotemporal dementia

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Katharina Waury; [2020]
    Keywords : Bioinformatics; Proteomics; Dementia; FTD; Biomarker; Machine Learning; Random Forest; R; Pipeline;

    Abstract : Frontotemporal dementia is a neurodegenerative disorder with high heterogeneity on the genetic, pathological and clinical level. The familial form of the disease is mainly caused by pathogenic variants of three genes: C9orf72, MAPT and GRN. READ MORE

  6. 5. Proteomics Study of a Designed Nanoparticle-Protein Corona Made of Animal Model Plasma

    University essay from Linköpings universitet/Institutionen för fysik, kemi och biologi

    Author : Elin Nilsson; [2020]
    Keywords : Nanoparticle; Protein corona; Nanoparticle-protein corona; SUrface proteomics; Safety; Targeting; and Uptake;

    Abstract : Nanoparticles are currently finding increasing use as drug delivery systems in the treatment of cancer and other disorders. When nanoparticles are introduced into body fluids, they adsorb proteins forming a coating called protein corona. READ MORE