Essays about: "Gene network topology"

Found 3 essays containing the words Gene network topology.

  1. 1. CONNECTING THE DOTS : Exploring gene contexts through knowledge-graph representations of gene-information derived from scientific literature

    University essay from KTH/Skolan för elektroteknik och datavetenskap (EECS)

    Author : Henrietta Hellberg; [2023]
    Keywords : Knowledge graph construction; Information extraction; Knowledge Graphs; Next-Generation Sequencing; Gene contextualization; Kunskapsgrafkonstruktion; Informationsextraktion; Kunskapsgrafer; Next-Generation Sequencing; Kontextualisering av gener;

    Abstract : Analyzing the data produced by next-generation sequencing technologies relies on access to information synthesized based on previous research findings. The volume of data available in the literature is growing rapidly, and it is becoming increasingly necessary for researchers to use AI or other statistics-based approaches in the analysis of their datasets. READ MORE

  3. 2. Modelling of gene regulatory and spatial mechanisms which pattern the early human neural tube

    University essay from Lunds universitet/Beräkningsbiologi och biologisk fysik - Genomgår omorganisation

    Author : Fredrik Bertilsson; [2022]
    Keywords : Biophysics; systems biology; gene regulatory networks; neural tube; isthmic organizer; midbrain-hindbrain boundary; WNT; FGF; morphogens; reaction-diffusion; finite-difference; 3D modelling; Physics and Astronomy;

    Abstract : Tissue patterning during development is thought to be driven largely by gene regulatory responses to spatial gradients of molecular signals, known as morphogens. In this thesis, early patterning of the human neural tube is studied using two different gene regulatory network models. READ MORE

  4. 3. Modelling conversion of adult skin cells to neurons

    University essay from Lunds universitet/Institutionen för astronomi och teoretisk fysik - Genomgår omorganisation; Lunds universitet/Beräkningsbiologi och biologisk fysik - Genomgår omorganisation

    Author : Viktor Drugge; [2018]
    Keywords : Human adult fibroblast; Neuron; Neural conversion; Transdifferentiation; Direct reprogramming; Direct lineage conversion; Simulation; Regulatory gene network; Gene network topology; Gene circuit; Gene dynamics; Physics and Astronomy;

    Abstract : Scientists are now able to directly convert one somatic cell type into another using a procedure known as direct lineage reprogramming or transdifferentiation. In this procedure, transcription factors which are important for initiating a rewriting of the gene expressions are introduced in the cell. READ MORE