Essays about: "Kinases"

Showing result 1 - 5 of 26 essays containing the word Kinases.

  1. 1. Regulatory Driven Clustering of Single-Cell Data; Clustering of single-cell RNA sequencing from glioblastoma with a novel mathematical method

    University essay from Göteborgs universitet/Institutionen för matematiska vetenskaper

    Author : Kári Kristjánsson; [2023-08-08]
    Keywords : ;

    Abstract : Cancer is a leading cause of death worldwide. Single-cell RNA sequencing has arisen as an important method to explore the gene expression of biological cells, including cancer cells. In this study, we deployed a computational algorithm known as ScRegClust to dissect single-cell RNA-sequencing (scRNA-seq) data from brain tumors. READ MORE

  3. 2. Effects of phosphorylation on the ADP-ribosylation activity of PARP16

    University essay from Lunds universitet/Kemiska institutionen

    Author : Virginia Martín Cristóbal; [2023]
    Keywords : ADP-ribosylation; Kinases; PARP16; Phosphorylation; UPR biochemistry; Biochemistry; Chemistry;

    Abstract : PARP16/ARTD15 is an intracellular mono-ADP-ribosyltransferase that catalyzes auto- and heteromodification by transfer of a single ADP-ribose moiety. It belongs to the ADP-ribosyltransferase (ART) superfamily. READ MORE

  4. 3. Ligand-stimulated cleavage of PDGFR-beta

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Agni Karolina Tsiatsiou; [2023]
    Keywords : ;

    Abstract : Platelet-derived growth factor receptors (α and β) are included in the family of receptor tyrosine kinases (RTKs). The dimeric PDGF ligands bind to the PDGF receptors and this results in receptor dimerization, autophosphorylation, and thus activation. The autophosphorylated receptor dimer activates numerous signaling pathways. READ MORE

  5. 4. Bioinformatics analysis on the drug design supporting systems

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Emilia Guszpit; [2023]
    Keywords : ;

    Abstract : This research project investigates the interactions of staurosporine, a potent kinase inhibitor, with 11 ligands, highlighting its role in drug design and bioinformatics. Focusing on the selectivity and promiscuity of staurosporine in binding to protein kinases, the study employs the MANORAA database for data extraction. READ MORE

  6. 5. Regulation of Plant Defense Genes Against Bacterial Pathogens

    University essay from KTH/Proteinvetenskap

    Author : Jenny Sjöström; [2021]
    Keywords : plant defense; PTI; FLS2; SERK1; regulation; växtförsvar; PTI; FLS2; SERK1; reglering;

    Abstract : Sjukdom på grödor orsakad av bakterier kan bidra till ekonomiska förluster för bönder samt brist på mat, därför är det viktigt att utveckla nya hållbara sätt att motverka och behandla grödor mot bakterier. Idag är det mest vanliga tillvägagångssättet antibiotika men detta är inte hållbart p.g.a uppkomst av antibiotikaresistens. READ MORE