Essays about: "Multiple Sequence Alignment"

Showing result 1 - 5 of 13 essays containing the words Multiple Sequence Alignment.

  1. 1. Prediction of multiple conformational states of membrane proteins

    University essay from Linköpings universitet/Bioinformatik

    Author : Tobias Thorén; [2024]
    Keywords : Bioinformatics; Protein prediction; AlphaFold;

    Abstract : Predicting protein structures has long been an area of active research in the field ofbioinformatics. Great strides have recently been made in this area by googles DeepMindteam. They developed an AI called AlphaFold which is able to make the most accuratepredictions of protein structures as of date. READ MORE

  3. 2. Determining Protein Conformational Ensembles by Combining Machine Learning and SAXS

    University essay from KTH/Tillämpad fysik

    Author : Samuel Eriksson Lidbrink; [2023]
    Keywords : AlphaFold; AlphaFold2; SAXS; protein conformational ensembles; machine learning; protein conformations; reweighting; SAXS; AlphaFold; AlphaFold2; proteinkonformationsensembler; maskininlärning; proteinkonformationer; omviktning;

    Abstract : In structural biology, immense effort has been put into discovering functionally relevant atomic resolution protein structures. Still, most experimental, computational and machine learning-based methods alone struggle to capture all the functionally relevant states of many proteins without very involved and system-specific techniques. READ MORE

  4. 3. Predicting Protein Stability with Machine Learning

    University essay from Lunds universitet/Biofysikalisk kemi

    Author : Lucas Carlsson; [2023]
    Keywords : Protein Stability; Biophysical Chemistry; Thermodynamics; Machine Learning; Deep Learning; Protein Language Model; Biochemistry; Multiple Sequence Alignment; Bioinformatics; Biology and Life Sciences;

    Abstract : Protein stability is a property of high importance and is of interest in a variety of fields. It determines if a protein has its native fold and can be of influence in certain diseases such as Parkinson's and Alzheimer's disease. READ MORE

  5. 4. Development of a Python Pipeline for the Analysis of Campylobacter

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Elvira Zetterberg; Evelina Andersson; Alma Nilsson; Moa Qvarnlöf; Corinne Olivero; Julia Sulyaeva; [2022]
    Keywords : Campylobacter; WGS; pipeline; sequence alignment; Illumina; ARIBA;

    Abstract : Statens veterinärmedicinska anstalt, SVA, is a government agency that works for better animal and human health with a primary focus on infectious animal diseases. One of their projects involves tracking the spread of Campylobacter infection in broilers and the occurrence of antimicrobial resistance in these bacteria. READ MORE

  6. 5. Evaluation and implementation of quality control parameters for genome-wide DNA methylome sequencing

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Sara Ekberg; [2022]
    Keywords : ;

    Abstract : Epigenomics is the study of modifications to the genetic material without changes to the DNA sequence, one such modification is methylation of nucleotides. DNA methylation is associated with gene regulation and is studied in a variety of fields such as cancer and ageing. READ MORE