Essays about: "RKO"

Found 2 essays containing the word RKO.

1. 1. ProTargetMiner one step further : Deep comparative proteomics of Dying vs. Surviving cancer cells treated with anticancer compounds

   University essay from Uppsala universitet/Analytisk kemi

   Author : Albin Lundin; [2022]
   Keywords : Cancer; Surviving VS Dying; Proteomics; Comparative Proteomics; RKO; A549; MCF7; drug discovery; life; death; life and death decisions; target ranking; OPLS-DA; drug targets; novel anticancer agents;

   Abstract : Cancer is a leading cause of mortality worldwide, responsible for nearly one in six deaths. Thus, there is a need for a greater understanding of cancer for the development of novel therapeutics. This master thesis project aims to compare the proteome signatures between dying and surviving cancer cells treated with diverse anticancer drugs. READ MORE

3. 2. PREPARATION AND CHARACTERIZATION OF BOVINE MEAT AND MILK FACTOR VESICLES/PARTICLES & IDENTIFICATION OF MSBI1 REP INTERACTING PROTEINS

   University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

   Author : Farhana Manzoor; [2020]
   Keywords : Bovine meat and milk factors; multiple sclerosis; immunoprecipitation co-immunoprecipitation; protein dimers; mass spectrometry; immunodetection; cesium chloride density gradient centrifugation; sodium dodecyl sulfate-polyacrylamide gel electrophoresis; vesicle; particle; interaction partner; pull-down assay.;

   Abstract : Introduction: Bovine meat and milk factors (BMMF) frequently isolated from bovine meat and milk, are discussed as putative causative agents for breast, colon and possibly other cancers. The hypothesis was formulated based on earlier correlative studies indicating that BMMFs could indirectly trigger inflammation, accumulate mutational events via reactive oxygen and nitrogen species production which eventually provokes tumor formation. READ MORE