Essays about: "crispr"

Showing result 16 - 20 of 66 essays containing the word crispr.

  1. 16. Novel mRNA therapeutics for cardiomyogenesis and vasculogenesis

    University essay from KTH/Proteinvetenskap

    Author : Xiaoting Huang; [2022]
    Keywords : Heart; Placental growth factor PLGF ; Cardiomyogenesis; Vasculognesis; Regeneration; hjärta; PLGF; kardiomyogenes; vaskulogenes; regenerering;

    Abstract : Kardiovaskulära sjukdomar är fortfarande en av de främsta dödsorsakerna i dag. Den främsta orsaken till sjukdomen är skador på hjärtcellerna, som kanske inte kan repareras av sig själva, så att utveckla en ny terapi för att regenerera eller reparera hjärtcellerna är ett viktigt mål inom forskningen om hjärtsjukdomar. READ MORE

  3. 17. Validation of enhancer variants modulating haematological toxicity reactions

    University essay from KTH/Proteinvetenskap

    Author : Zandra Norberg; [2022]
    Keywords : Chemotherapy; haematological toxicity reaction; enhancer variants; CRISPRi; K562; Cytostatika; hematologiska toxicitetsreaktioner; enhancer-varianter; CRISPRi; K562;

    Abstract : Omkring 20 miljoner nya cancerfall inträffar över hela världen varje år, och under 2020 uppskattades det att 10 miljoner dödsfall var förknippade med cancer. En av de vanligaste behandlingarna för cancer är cytostatika (cellgifter) som angriper alla snabbväxande celler. READ MORE

  4. 18. CRISPR AND THETREATMENT/EN DISTINCTION : On Vagueness, Borderline Cases and Germline Genome Editing

    University essay from Umeå universitet/Institutionen för idé- och samhällsstudier

    Author : Ellen Svensson; [2021]
    Keywords : CRISPR; Treatment; Enhancement; Vagueness; Borderline cases; Slippery slope; Germline genome editing; GGE; Gene editing; Distinction; Ethics; Radical Enhancement; Human Nature; Eugenics;

    Abstract : In this thesis, I argue that the treatment/enhancement distinction that is central to the ethical debate concerning germline genome editing and CRISPR is too vague to be ethically and normatively guiding. The problem of vagueness is twofold, being both a semantic and epistemic issue. READ MORE

  5. 19. Generation of induced pluripotent stem cells (iPSCs) lines deficient for genes associated with neurodevelopmental diseases using CRISPR/Cas9 technology

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Claudia De Guidi; [2021]
    Keywords : ;

    Abstract : Induced pluripotent stem cells (iPSCs) can self-renew and differentiate into many other cell types. IPSCs are derived from somatic cells, and upon reprogramming, they share an expression profile similar to embryonic stem cells (ESCs). READ MORE

  6. 20. Potential Application of Multiplex Automated Genome Engineering (MAGE) and One-Step Curing Plasmid System for Environmental Cambodian Enterobacterial Isolates

    University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Author : Olivia Alexandra; [2021]
    Keywords : Antimicrobial resistance; plasmid curing; environmental isolates; recombineering; enterobacteria;

    Abstract : Antimicrobial resistance (AMR) is concerning because it limits antimicrobial drug treatment options. AMR occurs by the overuse and misuse of antimicrobial drugs. In environmental settings, AMR can disseminate from places of high use, which leads to increased exposure to humans and animals. READ MORE