Essays about: "electrophoretic mobility."

Showing result 1 - 5 of 7 essays containing the words electrophoretic mobility..

  1. 1. Investigation of the function of the SH3-like domain of the Saccharopolyspora erythraea iron-dependent regulator

    University essay from Uppsala universitet/Institutionen för kemi - BMC

    Author : Carita Hammar; [2022]
    Keywords : ;

    Abstract : The bacterium Saccharopolyspora erythraea is utilized to produce the widely used antibiotic erythromycin. With the increasing problem of antibiotic resistance, the development of derivatives of the drug is of great importance. To produce antibiotics biosynthetically, it is crucial to understand the metabolic pathways utilized by the bacterium. READ MORE

  3. 2. Non-coding constraint mutations impact the gene regulatory system in osteosarcoma

    University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi; Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Raphaela Pensch; [2021]
    Keywords : cancer; osteosarcoma; cancer genomics; evolutionary constraint; non-coding mutations; gene regulation;

    Abstract : The non-coding space makes up around 98 % of the genome, but cancer-driving mutations have so far mostly been discovered in protein-coding regions. The majority of somatic non-coding mutations are neutral passenger mutations and identifying non-coding mutations with driving roles in cancer poses a challenge. READ MORE

  4. 3. Characterization of DNA binding of the two zinc finger domains of transcription factor zBED6

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Alexander Taubert; [2019]
    Keywords : transcription factor; zinc finger; zBED6;

    Abstract : The zinc finger protein, zBED6, is a transcriptional regulator of IGF2 along with hundreds of other genes relating to development and growth. Studies on the growth of commercially bred pigs discovered a single nucleotide substitution in the third intron of IGF2 which disrupts the binding of zBED6 and is responsible for the three-fold upregulation of IGF2 in skeletal muscle. READ MORE

  5. 4. Synthesis and characterization of amine-functionalized microgel particles and their subsequent assembly into colloidal molecule-like clusters by droplet-based microfluidics

    University essay from Lunds universitet/Kemiska institutionen

    Author : Emil Gustafsson; [2015]
    Keywords : Physical chemistry; fysikalisk kemi; Chemistry;

    Abstract : The ability of thermoresponsive, amine-functionalized microgel particles to take part in microgelmicrogel inter-cross-linking has previously been reported in the literature, in connection to applications such as for example the formation of stimuli-responsive colloidal gels and colloidosomes [1]. This thesis deals with the synthesis of such thermoresponsive, cross-linkable microgels and their subsequent assembly into clusters using droplet-based microfluidics, with the goal of forming responsive colloidal molecules with well-defined valency. READ MORE

  6. 5. Nanoparticle-based capillary electrochromatography

    University essay from Lunds universitet/Kemiska institutionen

    Author : Atef Mannaa; [2013]
    Keywords : PSP-CEC; UV; MALDI-TOF MS; Chemistry;

    Abstract : In this work, lipid nanoparticles were used as pseudostationary phase, PSP, for protein separation in capillary electrochromatography, CEC. The aim of the work was to use a new analytical separation technique for future analysis of protein drugs by using lipid nanoparticles as a pseudo-stationary phase with conventional UV-detection. READ MORE