Essays about: "gemcitabin"

Found 3 essays containing the word gemcitabin.

1. 1. Combining doxorubicin and gemcitabine with targeted drugs as a treatment option for high-risk neuroblastoma

   University essay from KTH/Proteinvetenskap

   Author : Alexandra Johannesson; [2023]
   Keywords : neuroblastoma; doxorubicin; gemcitabine; targeted drugs; ATM; neuroblastom; doxorubicin; gemcitabin; målinriktade läkemedel; ATM;

   Abstract : Neuroblastom är en barncancer som uppstår ur det sympatiska nervsystemet och drabbar omkring 15 barn i Sverige varje år. Högriskvarianten är associerad med mycket hög dödlighet och risk för återfall, vilket tros ha att göra med att tumörernas ovanligt heterogena sammansättning tillåter resistenta subpopulationer att motstå konventionella behandlingsmetoder. READ MORE

3. 2. Knockout studies of Panc1 cells

   University essay from KTH/Tillämpad fysik

   Author : Martin Sundin; [2021]
   Keywords : PDAC; crosstalk; stroma; spheroid; western blot; viability; gemcitabine.; PDAC;  verh rning; stroma; sf roid; western blot; viabilitet; gemcitabine.;

   Abstract : Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal form of cancerwith very few available treatment options of which none has great effect.Cancer cells and stromal cells such as stellate cells which exist in abundancein PDAC interact by crosstalk, resulting in a tumorigenic collective response. READ MORE

4. 3. Circumventing Gemcitabine resistance in pancreatic cancer using drug delivery systems

   University essay from Lunds universitet/Examensarbeten i molekylärbiologi

   Author : Gabriella Willman; [2017]
   Keywords : Biology and Life Sciences;

   Abstract : Gemcitabine is the first line treatment of pancreatic cancer, a treatment that is relying on the expression of human Equilibrative Nucleoside Transporter 1 for cellular uptake. Combined with its short blood half-life and intracellular activation steps, Gemcitabine treatment has many limitations. READ MORE