Essays about: "protein scaffold"
Showing result 1 - 5 of 21 essays containing the words protein scaffold.
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1. The role of AmotL2 in the regulation of mesenchymal transitioning of endothelial cells
University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologiAbstract : Background During development, endothelial cells acquire mesenchymal-like properties to migrate and facilitate normal vascular formation. This process of transformation is known as endothelial to mesenchymal transition (EndMT) and has also been implicated in diseases like vascular pathologies contributing to endothelial inflammation, atherosclerosis and tumour angiogenesis. READ MORE
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2. Comparison of purifying DARPins using conventional methods and self-cleaving affinity chromatography
University essay from Uppsala universitet/BiokemiAbstract : An important issue in pharmaceutical industry is to develop processes to purify proteins. Thereare many purification methods that can be used for this purpose, but all methods have differentconstraints. READ MORE
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3. Engineered imaging scaffolds for cryo-EM of small proteins of interest
University essay from KTH/ProteinvetenskapAbstract : Strukturbestämning av proteiner är viktigt för att kunna förstå deras funktion och en snabbt utvecklande metod inom fältet är kryoelektronmikroskopi. Storleksbegränsningar förhindrar en bredare applikation av metoden eftersom små proteiner har för låg signal i förhållande till bakgrund för att kunna visualiseras som enstaka partiklar i elektronmiksoskopibilder. READ MORE
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4. Drug Design of β-Lactamase Inhibitors of the DBO-scaffold against OXA-48 : A Molecular Dynamics Study of Ligand Stability in the Michaelis Complex
University essay from Uppsala universitet/Läkemedelsdesign och läkemedelsutvecklingAbstract : The emergence of β-lactamase-mediated antibiotic resistance is one of the biggest threats in modern times. Combined with the discovery void of new forms of antibiotics, this sets the course toward a future where the efficacy of present-day health care will be jeopardized. READ MORE
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5. Pipeline for Next Generation Sequencing data of phage displayed libraries to support affinity ligand discovery
University essay from Uppsala universitet/Institutionen för immunologi, genetik och patologiAbstract : Affinity ligands are important molecules used in affinity chromatography for purification of significant substances from complex mixtures. To find affinity ligands specific to important target molecules could be a challenging process. Cytiva uses the powerful phage display technique to find new promising affinity ligands. READ MORE