Essays about: "Immunofluorescence IF"

Showing result 1 - 5 of 13 essays containing the words Immunofluorescence IF.

  1. 1. The role of AmotL2 in the regulation of mesenchymal transitioning of endothelial cells

    University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Author : Anita-Ann Monteiro; [2023]
    Keywords : Endothelial-mesenchymal transition EndMT ; atherosclerosis; transforming growth factor β TGF-β ; Angiomotin-Like 2 AmotL2 ; Scrambled Scr ; knockdown kd ; Immunofluorescence IF ;

    Abstract : Background During development, endothelial cells acquire mesenchymal-like properties to migrate and facilitate normal vascular formation. This process of transformation is known as endothelial to mesenchymal transition (EndMT) and has also been implicated in diseases like vascular pathologies contributing to endothelial inflammation, atherosclerosis and tumour angiogenesis. READ MORE

  3. 2. Establishing a 7-plex panel for diagnostic markers of lung cancers using multiplexed IF solutions

    University essay from KTH/Proteinvetenskap

    Author : Katarina Åstrand; [2022]
    Keywords : Lung cancer; Immunostaining; Multiplexed tissue imaging; Immunofluorescence; TSA; Lungcancer; immunofärgning; multiplexed vävnads imaging; immunofluorescence; TSA;

    Abstract : Lungcancer är en heterogen sjukdom som kräver många histopatologiska analyser för att diagnostisera och behandla effektivt. Dessa analyser utförs för närvarande med singelplex immunohistokemi (IHC) vilket kräver mycket vävnadsprovmaterial om flera markörer behöver färgas för. READ MORE

  4. 3. Cellular localization of the estrogen receptor GPER1 in colorectal cancer cell lines

    University essay from KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Author : Malin Lundvall; [2022]
    Keywords : colon cancer; GPER1; estrogen receptor; IF;

    Abstract : Colorectal cancer is the third most common cancer type in the world with a mortality rate of around 2000 people in Sweden, year 2018. Women tend to have a lower risk of developing and progressing colorectal cancer, specifically premenopausal women. This indicates that Estrogen plays an important role in protecting from colorectal cancer. READ MORE

  5. 4. VISUALIZING CATESTATIN AND CHROMOGRANIN A : An Antibody Validation

    University essay from Uppsala universitet/Institutionen för medicinsk cellbiologi

    Author : Johan William-Olsson; [2022]
    Keywords : Diabetes; immunology; western blot; flow cytometry; immunofluorescence;

    Abstract : Chromogranin A (CgA) and its cleavage product Catestatin (CST) are two very interesting proteins, especially due to their possible involvement in the development of type 1 diabetes. There are currently only a few primary antibodies against CgA and CST, and the ones that do exist are often only recommended for use on one method. READ MORE

  6. 5. Identification of changes in biomarkers relevant for breast cancer biology occurring in a novel 3D-Biosilk model

    University essay from KTH/Proteinvetenskap

    Author : Emmy Ståhl; [2021]
    Keywords : 3D-Biosilk; breast cancer; 3D cell culture; recombinant spider silk; ZO-1; 3D-Biosilk; bröstcancer; 3D cellkultur; rekombinant spindeltråd; ZO-1;

    Abstract : Bröstcancer är den vanligaste formen av cancer som drabbar kvinnor. Det är en heterogen och komplex sjukdom som består av flera undergrupper, var och en med distinkt morfologi och kliniska implikationer [1]. För att modellera och studera cellbiologi, vävnadsmorfologi, molekylära mekanismer och läkemedels effekter används cellkulturer [2]. READ MORE