Essays about: "tissue specific gene expression"

Showing result 1 - 5 of 20 essays containing the words tissue specific gene expression.

  1. 1. How molecular diagnostics based on gene expressions can improve diagnostics in Sarcoma

    University essay from Lunds universitet/Avdelningen för Biomedicinsk teknik

    Author : Emma Friberg; Alma Lennartsson; [2023]
    Keywords : Technology and Engineering;

    Abstract : Sarcoma, a rare and heterogeneous cancer type, present significant diagnostic challenges due to its numerous subtypes. Molecular diagnostics and machine learning models have emerged as promising tools to enhance sarcoma diagnosis. READ MORE

  3. 2. Transcriptional basis of Huntington’s Disease: Gene expression analysis indicate increased immune responses in the brain and mitochondrial dysfunction in adipose tissues of HD model mouse

    University essay from KTH/Proteinvetenskap

    Author : Intisar Salim; [2023]
    Keywords : Huntington’s Disease; mRNA-seq; tissue specific gene expression; cerebrospinal fluid; biomarker; Huntingtons sjukdom; mRNA-seq; vävnadsspecifik genexpression; cerebrospinalvätska; biomarkör;

    Abstract : Huntingtons sjukdom (HD) är ett neurodegenerativt tillstånd som orsakas av mutationer i huntingtin gen (Htt), och resulterar till upprepade glutamin (polyQ) i Htt-proteinet. Muterad Htt kan inte vika sig ordentligt och börjar därför aggregera i celler. READ MORE

  4. 3. Energy Landscapes for Early T Cell Development

    University essay from Lunds universitet/Beräkningsbiologi och biologisk fysik - Genomgår omorganisation

    Author : Yukun Cheng; [2022]
    Keywords : Physics and Astronomy;

    Abstract : T cell lineage development from an early thymic progenitor involves programmed shutoff of progenitor gene expression, upregulation of T cell specification genes, and proliferation. This biological system has been deeply studied and a gene regulatory network (GRN) that can accurately describe the system has been presented. READ MORE

  5. 4. Cancer Driver Gene Detection using Deep Convolutional Neural Networks on H3K4me3 Enrichment Profiles

    University essay from Lunds universitet/Institutionen för astronomi och teoretisk fysik - Genomgår omorganisation

    Author : Marc Pielies Avellí; [2022]
    Keywords : Cancer Driver CD Gene; Histone Post-Translational Modifications PTMs ; Convolutional Neural Networks CNNs .; Physics and Astronomy;

    Abstract : In spite of our current knowledge regarding the biology underlying cancer genesis, reliable methods for the discovery of cancer driver (CD) genes are still in great need. The rather recent incorporation of epigenetic markers to the cancer paradigm has nevertheless opened the door for the development of new computational approaches to the problem. READ MORE

  6. 5. The role of P25 interacting transcriptional regulator VIP1 in activation of transcription.

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Asma Kanon Hashi; [2022]
    Keywords : Rhizomania; BNYVV; expression clones; virulence factor P25; transcription; transient gene expression; VIP1 plant protein;

    Abstract : Rhizomania, caused by beet necrotic yellow vein virus (BNYVV), has been considered as an economically important disease around the world because of the extreme reduction in sugar beet yield and sugar content in affected plants. The spread of rhizomania all over the world, including the emergence of resistance- breaking virus isolates, have been become a major concern for the plant pathologists and plant breeders aiming at improving sugar beet resistance to   BNYVV as well as better understanding sugar beet-virus interactions during disease development. READ MORE