Essays about: "tumour markers"
Showing result 1 - 5 of 11 essays containing the words tumour markers.
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1. Predicting tumour growth-driving interactions from transcriptomic data using machine learning
University essay from Uppsala universitet/Neuroonkologi och neurodegenerationAbstract : The mortality rate is high for cancer patients and treatments are only efficient in a fraction of patients. To be able to cure more patients, new treatments need to be invented. Immunotherapy activates the immune system to fight against cancer and one treatment targets immune checkpoints. READ MORE
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2. The role of AmotL2 in the regulation of mesenchymal transitioning of endothelial cells
University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologiAbstract : Background During development, endothelial cells acquire mesenchymal-like properties to migrate and facilitate normal vascular formation. This process of transformation is known as endothelial to mesenchymal transition (EndMT) and has also been implicated in diseases like vascular pathologies contributing to endothelial inflammation, atherosclerosis and tumour angiogenesis. READ MORE
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3. Molecular mapping of the HGSOC tumour microenvironment
University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologiAbstract : High-grade serous ovarian cancer (HGSOC) is the most aggressive subtype of ovarian cancer, and its heterogeneity poses a challenge for the discovery of reliable diagnostic biomarkers, therapeutic targets, and predicting treatment response, particularly to immunotherapy. The current standard diagnostic and treatment options are inadequate, resulting in late diagnosis and poor prognosis. READ MORE
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4. The Role of Endoplasmic Reticulum Stress and Hepatic Stellate Cells in Inducing Chemoresistance in Hepatocellular Carcinoma
University essay from Uppsala universitet/Institutionen för medicinsk cellbiologiAbstract : Hepatocellular carcinoma (HCC) is the most common liver malignancy that usually develops in patients suffering from chronic liver diseases. One of the major problems faced in the treatment of HCC is severe chemoresistance. READ MORE
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5. Analysis of single cell RNA seq data to identify markers for subtyping of non-small cell lung cancer
University essay from Högskolan i Skövde/Institutionen för biovetenskapAbstract : Single cell RNA technology is a recent technical advancement used to understand the cancertumorgenicity at single cell resolution. In this study we have analyzed the scRNA data from thenon-small cell lung cancer (NSCLC) dataset to facilitate the early identification of NSCLCsubtypes namely, squamous cell carcinoma (SCC) and adenocarcinoma (AC). READ MORE