Essays about: "cancer genetics"

Showing result 1 - 5 of 11 essays containing the words cancer genetics.

  1. 1. Cancer Driver Gene Detection using Deep Convolutional Neural Networks on H3K4me3 Enrichment Profiles

    University essay from Lunds universitet/Institutionen för astronomi och teoretisk fysik - Genomgår omorganisation

    Author : Marc Pielies Avellí; [2022]
    Keywords : Cancer Driver CD Gene; Histone Post-Translational Modifications PTMs ; Convolutional Neural Networks CNNs .; Physics and Astronomy;

    Abstract : In spite of our current knowledge regarding the biology underlying cancer genesis, reliable methods for the discovery of cancer driver (CD) genes are still in great need. The rather recent incorporation of epigenetic markers to the cancer paradigm has nevertheless opened the door for the development of new computational approaches to the problem. READ MORE

  3. 2. Identification of novel loss of heterozygosity collateral lethality genes for potential applications in cancer

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Margus Veanes; [2021]
    Keywords : biology; oncology; structural; genetics; bioinformatics; cancer;

    Abstract : Over the course of this project, I demonstrate the utility of a 4-phase analysis pipeline in the context of cancer therapy and the associated search for antineoplastic drug candidates. I showcase a repeatable means for generating lists of potential targets which may be used in conjunction with methods like small molecule screening as part of a search for broadly effective antineoplastic agents. READ MORE

  4. 3. Cost-Effectiveness of Surveillance Programs of Carriers of Pathogenic Mutations in the TP53-Gene in Sweden

    University essay from Linköpings universitet/Nationalekonomi

    Author : Oskar Frisell; [2020]
    Keywords : TP53 Surveillance Cost-effectiveness Genetics;

    Abstract : Introduction: Pathogenic mutations in the TP53-gene is present in about 50% of all somatic cancers. The TP53 gene’s function is to stop cancer cells from dividing, thus protect us from cancer. When this gene is not functioning properly, carriers face 70-100% risk of developing cancer in their lifetime. READ MORE

  5. 4. Epigenetiskt arv

    University essay from SLU/Dept. of Animal Breeding and Genetics

    Author : Moa Lindell; [2019]
    Keywords : epigenetik; epigenetisk nedärvning; epigenetiska mekanismer;

    Abstract : Epigenetik är den del av genetiken som behandlar förändringar i genuttryck som är oberoende av förändringar i DNA-sekvensen. Det som styr vilka gener som uttrycks och får effekt på fenotyp har studerats av forskare sedan 70-80-talet. READ MORE

  6. 5. Investigation of RRM2 as a potential therapeutic target against glioblastoma

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Neda Hekmati; [2017]
    Keywords : cancer; glioblastoma; RRM2;

    Abstract : Title: Investigation of RRM2 as a potential therapeutic target against glioblastoma Supervisors: Dr. Sven Nelander and Mr. Sathishkumar Baskaran. READ MORE