Essays about: "protein dimers"

Showing result 1 - 5 of 6 essays containing the words protein dimers.

  1. 1. Modelling Large Protein Complexes

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Ho Yeung Chim; [2023]
    Keywords : Protein Modeling; Monte Carlo Tree Search; Protein Complex;

    Abstract : AlphaFold [Jumper et al., 2021, Evans et al., 2022] is a deep learning-based method that can accurately predict the structure of single- and multiple-chain proteins. However, its accuracy decreases with an increasing number of chains, and GPU memory limits the size of protein complexes that can be predicted. READ MORE

  3. 2. Investigation of the function of the SH3-like domain of the Saccharopolyspora erythraea iron-dependent regulator

    University essay from Uppsala universitet/Institutionen för kemi - BMC

    Author : Carita Hammar; [2022]
    Keywords : ;

    Abstract : The bacterium Saccharopolyspora erythraea is utilized to produce the widely used antibiotic erythromycin. With the increasing problem of antibiotic resistance, the development of derivatives of the drug is of great importance. To produce antibiotics biosynthetically, it is crucial to understand the metabolic pathways utilized by the bacterium. READ MORE

  4. 3. Structure-based design of novel pharmacological tools for the A3 adenosine G protein-coupled receptor

    University essay from Uppsala universitet/Institutionen för läkemedelskemi

    Author : Ashish Tamhankar; [2021]
    Keywords : ;

    Abstract : Adenosine receptors (ARs) are a family belonging to the GPCR superfamily, involved with multiple physiological processes and widely distributed throughout the body. In this study, we focus on the A3 AR due to its vast scale applications in various pathophysiological conditions such as inflammation, pain, allergic asthma, and cancer chemotherapy. READ MORE

  5. 4. PREPARATION AND CHARACTERIZATION OF BOVINE MEAT AND MILK FACTOR VESICLES/PARTICLES & IDENTIFICATION OF MSBI1 REP INTERACTING PROTEINS

    University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Author : Farhana Manzoor; [2020]
    Keywords : Bovine meat and milk factors; multiple sclerosis; immunoprecipitation co-immunoprecipitation; protein dimers; mass spectrometry; immunodetection; cesium chloride density gradient centrifugation; sodium dodecyl sulfate-polyacrylamide gel electrophoresis; vesicle; particle; interaction partner; pull-down assay.;

    Abstract : Introduction: Bovine meat and milk factors (BMMF) frequently isolated from bovine meat and milk, are discussed as putative causative agents for breast, colon and possibly other cancers. The hypothesis was formulated based on earlier correlative studies indicating that BMMFs could indirectly trigger inflammation, accumulate mutational events via reactive oxygen and nitrogen species production which eventually provokes tumor formation. READ MORE

  6. 5. Recombinant expression of the cowpea chlorotic mottle virus

    University essay from Lunds universitet/Kemiska institutionen

    Author : Amanda Willas; [2019]
    Keywords : Biokemi; Biochemistry; Viruskapsid; Viruscaspid; CCMV; Chemistry;

    Abstract : All viruses are composed of both genetic material and a capsid. The capsid is composed by identical protein subunits and the purpose is protection of the genetic material, in this case RNA. READ MORE