Essays about: "Isabell Lindahl"

Found 2 essays containing the words Isabell Lindahl.

  1. 1. The Binding Mechanism of Carbapenems in the Class A beta-lactamase IMI-1 : A Molecular Dynamics Study of Ligand Stability

    University essay from Uppsala universitet/Biokemi

    Author : Isabell Lindahl; [2022]
    Keywords : antibiotic resistance; IMI-1; betalactamase; Carbapenemase; free energy; LIE; linear interaction energy; β-lactamase; meropenem; biapenem; imipenem; active site;

    Abstract : Antibiotic resistance is a global and accelerating matter. Over time, the bacteria have evolved several defense mechanisms against the antibiotics. One of the defense mechanisms is that the bacteria can produce enzymes with the ability to hydrolyze the characteristic b-lactam ring of the antibiotics. These enzymes are called b-lactamases. READ MORE

  3. 2. An investigation of aspects affecting availability and grading of high-risk antibiotics in Sweden. : Group 3

    University essay from Uppsala universitet/Institutionen för teknikvetenskaper

    Author : Isabell Lindahl; Samira Hilowle; Karlsson Viktor; Kåreceus Gustaf; [2019]
    Keywords : PLATINEA;

    Abstract : The aim of this report is to investigate aspects affectingavailability and grade high-risk antibiotics in Sweden. 10antibiotics out of 39 antibiotics compiled by the Swedish PublicHealth Authority were studied according to the factors; class(based on chemical structure), industrial production process,number of API manufacturers found, the geographic location of the API manufacturers, number of MAH found in Sweden, number of MAH found in the EEA, number of backorders in Sweden, total length of backorders, currently not provided in Sweden (Number of MAH), assumed profitability per product, uncertainty in annual sales volume (relative standard deviation), uncertainty in annual sales (relative standard deviation), average sales (High/Low) and lastly parallel import to Sweden. READ MORE