Essays about: "Mitochondrial diabetes"

Showing result 1 - 5 of 10 essays containing the words Mitochondrial diabetes.

  1. 1. Structural and Functional Characterisation of the Human Mitochondrial Pyruvate Carrier

    University essay from Lunds universitet/Kemiska institutionen

    Author : Simon Gripvall; [2023]
    Keywords : biochemistry; complex; MPC; proteoliposomes; pyruvate; transport; Chemistry;

    Abstract : The metabolism of pyruvate in the cell is abnormally regulated in several human diseases, such as type-II diabetes, cancer and neurodegenerative disorders, in which the human mitochondrial pyruvate carrier (HuMPC) sits at a pivotal point. It transports pyruvate across the inner mitochondrial membrane and consists of two proteins, MPC1 and MPC2, and is a potential drug target against these diseases. READ MORE

  3. 2. METABOLIC CRISIS IN humans WITH MITOCHONDRIAL DIABETES : DEVELOPMENT OF AN EX VIVO MODEL IN HUMAN BLOOD CELLS UNDER THE INFLUENCE OF ANTI-DIABETics

    University essay from Malmö universitet/Institutionen för biomedicinsk vetenskap (BMV)

    Author : Filippa Dahlgren; [2023]
    Keywords : Anti-diabetics; ATP-production; Metabolic crisis; Mitochondrial diabetes; Respiration;

    Abstract : Mitochondria are found in all cells of the body except red blood cells. Mitochondria is the organelle that produces the most ATP in the body, which is the cells energy carrier. All processes in the body require energy in one way or another, hence the function of mitochondria is very important. READ MORE

  4. 3. Expression and purification of pyruvate transporting human mitochondrial pyruvate carrier (MPC) protein complex for structural studies

    University essay from Lunds universitet/Examensarbeten i molekylärbiologi

    Author : Markus Wendler; [2022]
    Keywords : Biology and Life Sciences;

    Abstract : Pyruvate is one of the main molecules needed for the citric acid cycle, which produces energy in the form of ATP. The citric acid cycle reaction occurs in the mitochondrial matrix, and for pyruvate to participate in the reaction, it needs to be transported from the cytosol across the mitochondrial membranes into the mitochondrial matrix. READ MORE

  5. 4. Factors and mechanisms associating the mobilisation of Ca2+ with the activation of the NLRP3 inflammasome : A systematic review

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Maria Panagiota Theodorou; [2022]
    Keywords : ;

    Abstract : Inflammasomes are multiprotein complexes that play a critical role in the regulation of inflammation and the inflammatory responses against pathogens. NLRP3 (NOD-, LRR-and pyrin domain-containing protein 3) is among the molecules involved in the homonymous and well-studied NLRP3 inflammasome that accounts for the release of the pro-inflammatory cytokines interleukin (IL) 1-β and 18. READ MORE

  6. 5. Preparation of Pancreatic EndoCβH1 cells alone and together with Boundary Cap Neural Crest Stem cells for a microgravity experiment

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : SRINIVASAPRASAD RANGASWAMY; [2022]
    Keywords : Pancreatic Islets; Neural crest stem cells; space chamber; Survival test for EndoCβH1 cells; 3-D print;

    Abstract : Migrating to Mars is the next exploration of human space missions and adapting to the extreme environment for a long period of time needs to be studied in-prior. Studies on cells in space may promote advancements in our understanding of the human body. READ MORE