Essays about: "Tight junctions"

Showing result 1 - 5 of 11 essays containing the words Tight junctions.

1. 1. Investigation on Cell-Cell Junctions by Inhibition of Na,K-ATPase Activity

   University essay from KTH/Tillämpad fysik

   Author : Caroline Boström; [2021]
   Keywords : NaK-ATPase; Ouabain; Cell junctions; ECadherin; Occludin; Claudin7; Western Blot; Fluorescent Imaging; Tight junctions; Adherens Junctions; Immunocytochemistry; Ouabain; NaK-ATPase; ECadherin; Occludin; Claudin7; Western Blot; Immunocytokemi; Cellkontakter; Fluorescernsmikroskopi;

   Abstract : This thesis report investigates the effect on cellcell junction proteins when the Na,K-ATPase (NKA) is inhibited. The main goal is to develop an understanding of how the NKA activity regulates the cell junction proteins. The investigated proteins are the adherens junction protein ECadherin, and the tight junction proteins Occludin and Claudin7. READ MORE

3. 2. Models for predicting efflux transport over the blood-brain barrier

   University essay from Uppsala universitet/Institutionen för farmaci

   Author : Marjaneh Janani; [2020]
   Keywords : efflux transport; brain; blood-brain-barrier; Verapamil; Risperidone; Prazosin;

   Abstract : Aim: The general aim of this research is development and evaluation of novel methods for predicting active transport over the human blood-brain-barrier (BBB), while this project specifically aims to i) review the literature and select suitable methods and substrates, ii) develop models for determining in vitro kinetic properties of selected compounds, analyze the in vitro data using the developed models and to use Maximum Transport Activity (MTA) approach (Karlgren et al., 2012), iii) perform Physiology Based Pharmacokinetic (PBPK) modelling and compare to in vivo literature data. READ MORE

4. 3. Models for predicting efflux transport over the blood-brain barrier

   University essay from Uppsala universitet/Institutionen för farmaceutisk biovetenskap

   Author : Marjaneh Janani; [2020]
   Keywords : Efflux; blood-brain-barrier; modeling; transporter;

   Abstract : Aim: The general aim of this research is development and evaluation of novel methods for predicting active transport over the human blood-brain-barrier (BBB), while this project specifically aims to i) review the literature and select suitable methods and substrates, ii) develop models for determining in vitro kinetic properties of selected compounds, analyze the in vitro data using the developed models and to use Maximum Transport Activity (MTA) approach (Karlgren et al., 2012), iii) perform Physiology Based Pharmacokinetic (PBPK) modelling and compare to in vivo literature data. READ MORE

5. 4. Kolhydratdigestion hos häst : icke-strukturella kolhydrater

   University essay from SLU/Dept. of Animal Nutrition and Management

   Author : Malin Arkå; [2018]
   Keywords : ekvin; foder; fodermedel; fruktaner; fång; kolik; magsår; stärkelse;

   Abstract : Hästar utfodras i dagsläget på ett sätt som inte är anpassat efter deras digestionsapparat. Det kan leda till sjukdomar såsom kolik, fång och magsår. De här sjukdomarna är vanligt förekommande och kan i vissa fall vara fatala. READ MORE

6. 5. Simulation of Majorana Bound States in Multi-Band Josephson Junction Nanowires

   University essay from Lunds universitet/Fasta tillståndets fysik; Lunds universitet/Fysiska institutionen

   Author : Georg Wolgast; [2017]
   Keywords : Physics and Astronomy;

   Abstract : Majorana bound states can be created at the ends of semiconducting nanowires using a combination of proximity-induced superconductivity, spin-orbit coupling and a magnetic eld. By adding a Josephson junction to this nanowire, four Majorana bound states can exist at the same time in the system. READ MORE