Essays about: "histone modification"

Found 5 essays containing the words histone modification.

  1. 1. Cancer Driver Gene Detection using Deep Convolutional Neural Networks on H3K4me3 Enrichment Profiles

    University essay from Lunds universitet/Institutionen för astronomi och teoretisk fysik - Genomgår omorganisation

    Author : Marc Pielies Avellí; [2022]
    Keywords : Cancer Driver CD Gene; Histone Post-Translational Modifications PTMs ; Convolutional Neural Networks CNNs .; Physics and Astronomy;

    Abstract : In spite of our current knowledge regarding the biology underlying cancer genesis, reliable methods for the discovery of cancer driver (CD) genes are still in great need. The rather recent incorporation of epigenetic markers to the cancer paradigm has nevertheless opened the door for the development of new computational approaches to the problem. READ MORE

  3. 2. Targeting the epigenetic state of refractory and relapsing acute myeloid leukaemia

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Ojong Tabi Ojong Besong; [2021]
    Keywords : ;

    Abstract : Acute myeloid leukaemia (AML) is a heterogeneous group of myeloid lineage malignancies arising from a spectrum of mutations. AML is characterized by the uncontrolled proliferation of clonal cells, which are unable to properly differentiate into mature myeloid cells. READ MORE

  4. 3. Histone modifications and their role in splicing

    University essay from Linköpings universitet/Biologi

    Author : Anna Wettermark; [2020]
    Keywords : Splicing; Spliceosome; Histone modifications; epigenetics; histone methylation; histone acetylation; histone phosphorylation; histone ubiquitination;

    Abstract : Splicing is the process when introns gets removed and exons are spliced together. This is an important step to form a clean mRNA with no unnecessary sequences that could interrupt protein synthesis. There are different types of splicing and some of them need a complex called spliceosome. READ MORE

  5. 4. Epigenetiskt arv

    University essay from SLU/Dept. of Animal Breeding and Genetics

    Author : Moa Lindell; [2019]
    Keywords : epigenetik; epigenetisk nedärvning; epigenetiska mekanismer;

    Abstract : Epigenetik är den del av genetiken som behandlar förändringar i genuttryck som är oberoende av förändringar i DNA-sekvensen. Det som styr vilka gener som uttrycks och får effekt på fenotyp har studerats av forskare sedan 70-80-talet. READ MORE

  6. 5. Histone modifications after DNA damage affect survival in Schizosaccharomyces pombe

    University essay from Institutionen för livsvetenskaper

    Author : Abdul Mateen Rajput; [2010]
    Keywords : Epigenetics; DNA damage; S. pombe; yeast; histone modification; chromatin; life sciences; gene deletion; gene tagging; pcr; mms; 4-nqo; brl1; brl2; Epigenetics، ڈی این اے کو نقصان، ایس pombe، خمیر، histone تبدیلی، chromatin، زندگی سائنس، جین خارج، جین ٹیگنگ، پی سی آر، ایم ایم ایس،; Epigenetik; DNA-skada; S. pombe; jäst; histon modifiering; kromatin biovetenskap; gendeletion; gen taggning; PCR; MMS; 4-nqo; brl1; brl2;

    Abstract : S. cerevisiae Ada2 and Bre1 has a role in histone post-translational modifications. Deletion of these genes causes deficiency in acetylation (Ada2) or ubiquitination (Bre1) of histones. Further, mutants lacking these genes or homologous genes showed different phenotypes in human and S. READ MORE