Essays about: "native protein"

Showing result 1 - 5 of 69 essays containing the words native protein.

  1. 1. Effects of mixed surfactant system on chemical and physical stability of human growth hormone

    University essay from Lunds universitet/Livsmedelsteknik och nutrition (master)

    Author : Karnsinee Viriyayudhakorn; [2023]
    Keywords : human growth hormone; surfactant; refolding; protein stability; physical degradation; chemical degradation; pharmaceutical technology; Technology and Engineering;

    Abstract : In protein formulation, addition of surfactants is commonly executed to enhance product stability and shelf-life. The reason is that surfactants can protect proteins against surface-induced aggregation. However, the interaction between surfactant and protein depends on the type of surfactant used. READ MORE

  3. 2. Recombinant expression and purification of sugar beet Phytoglobins in Escherichia Coli BL21 (DE3) including metabolic engineering of the heme biosynthesis

    University essay from Lunds universitet/Tillämpad biokemi; Lunds universitet/Beräkningskemi

    Author : Pennie Lindblom; Olivia Geel; [2023]
    Keywords : Phytoglobin; Heme; δ-ALA; qPCR; SDS-PAGE; Bacterial cultivation; Escherichia coli; BvPgb1.2; ÄKTA; Applied biochemistry; Biology and Life Sciences;

    Abstract : The protein hemoglobin (Hb) is vital for us humans to ensure enough oxygen replacement in the body. Hb-resembling proteins also exist in plants, these are called phytoglobins (Pgbs). Pgbs are very interesting since they can play a considerable role in the development of blood substitutes and iron supplements for human use. READ MORE

  4. 3. Methods to study device induced aggregation of proteins

    University essay from Lunds universitet/Livsmedelsteknik och nutrition (master)

    Author : Marie Therese von Wowern; [2023]
    Keywords : protein formulation; protein aggregation; insulin; silicone oil; syringe; shear stress; subvisible particle; size exclusion chromatography; flow imaging microscopy; pharmaceutical technology; Technology and Engineering;

    Abstract : This work developed a method for the investigation of how medical devices, such as syringes and needles, affect the formation of subvisible particles in a protein drug without excipients. Protein-based pharmaceuticals are well known to be sensitive to different kinds of stress, and exposure to stress during the use of this device is unavoidable. READ MORE

  5. 4. Sensitive Detection of Blood Biomarker Pentraxin 3 – Development and Comparison of Amperometric and Capacitive Biosensors in Flow-Injection Systems

    University essay from Lunds universitet/Bioteknik; Lunds universitet/Bioteknik (master)

    Author : Viktor Johansson; [2023]
    Keywords : Bioanalysis; Pentraxin 3; PTX3; FIA; Flow-injection analysis; Sepis; Electopolymerization; Self-assembling monolayer; Amperometry; Capacitance; Biotechnology; Medicine and Health Sciences; Biology and Life Sciences; Technology and Engineering;

    Abstract : Within clinical diagnostics there is always a need for innovative methods that are rapid, sensitive, and more accurate. In this study two bioanalytical systems have been evaluated for pentraxin 3 (PTX3) detection. READ MORE

  6. 5. Predicting Protein Stability with Machine Learning

    University essay from Lunds universitet/Biofysikalisk kemi

    Author : Lucas Carlsson; [2023]
    Keywords : Protein Stability; Biophysical Chemistry; Thermodynamics; Machine Learning; Deep Learning; Protein Language Model; Biochemistry; Multiple Sequence Alignment; Bioinformatics; Biology and Life Sciences;

    Abstract : Protein stability is a property of high importance and is of interest in a variety of fields. It determines if a protein has its native fold and can be of influence in certain diseases such as Parkinson's and Alzheimer's disease. READ MORE