Essays about: "two-electrode voltage clamp"

Found 2 essays containing the words two-electrode voltage clamp.

1. 1. Characterization of diazepam binding inhibitor as a structure-function tool for human ɣ-aminobutyric acid-A receptors

   University essay from KTH/Proteinvetenskap

   Author : Szabolcs Simon-Guth; [2023]
   Keywords : γ-Aminobutyric acid sub-type A receptors; diazepam binding inhibitor; receptor modulation; recombinant protein expression; two-electrode voltage clamp; dose-response curve; Gammaaminosmörsyrareceptor typ A; Diazepambindande hämmare; receptormodulering; reckmbinant proteinexpression; spänningsklämma med två elektroder; dosresponskurva;

   Abstract : Gammaaminosmörsyrareceptorer typ A (GABAAR) är pentameriska ligandstyrda kloridkanaler som uppvisar neurohämmande egenskaper. Därmed är de primära läkemedelsmål för flera ångestdämpande och lugnande läkemedel som används för att minska förekomsten av aktionspotential i neuroner. READ MORE

3. 2. Modulation of a model ligand-gated ion channel by amphetamine derivatives

   University essay from Uppsala universitet/Strukturbiologi

   Author : Emelia Karlsson; [2022]
   Keywords : pentameric ligand-gated ion channels; sTeLIC; electrophysiology; psychostimulants; amphetamine derivatives;

   Abstract : Pentameric ligand-gated ion channels are critical mediators of electrochemical signal transduction in neurons and other excitable cells, causing them to be important targets of psychoactive drugs. Structural data for these complex proteins are limited, particularly among eukaryotic family members and for the functionally critical open state. READ MORE