Essays about: "dose-response curve"

Showing result 1 - 5 of 11 essays containing the words dose-response curve.

  1. 1. Characterization of diazepam binding inhibitor as a structure-function tool for human ɣ-aminobutyric acid-A receptors

    University essay from KTH/Proteinvetenskap

    Author : Szabolcs Simon-Guth; [2023]
    Keywords : γ-Aminobutyric acid sub-type A receptors; diazepam binding inhibitor; receptor modulation; recombinant protein expression; two-electrode voltage clamp; dose-response curve; Gammaaminosmörsyrareceptor typ A; Diazepambindande hämmare; receptormodulering; reckmbinant proteinexpression; spänningsklämma med två elektroder; dosresponskurva;

    Abstract : Gammaaminosmörsyrareceptorer typ A (GABAAR) är pentameriska ligandstyrda kloridkanaler som uppvisar neurohämmande egenskaper. Därmed är de primära läkemedelsmål för flera ångestdämpande och lugnande läkemedel som används för att minska förekomsten av aktionspotential i neuroner. READ MORE

  3. 2. Polymer gel dosimetry with MRI-readout for 3D dose verification - detector characteristics and clinical applications

    University essay from Lunds universitet/Sjukhusfysikerutbildningen

    Author : Thi Guldhill; [2023]
    Keywords : Medicine and Health Sciences;

    Abstract : Background & Purpose: Radiation therapy is an essential treatment for cancer patients with the ultimate goal to deliver radiation doses to the tumour with precision while minimizing exposure to surrounding healthy tissues. Treatment verification is crucial to ensure the accuracy of radiation delivery, for instance by measuring the radiation dose distribution. READ MORE

  4. 3. Developing and validating assay-ready HEK-Blue CD40L cells : For a more flexible and faster screening of Affibody® molecules

    University essay from Uppsala universitet/Institutionen för farmaceutisk biovetenskap

    Author : Erika Könberg; [2022]
    Keywords : cell biology; assay-ready cells; HEK-Blue cells;

    Abstract : Cell assay that evaluates a biologics’ potency and efficacy is an important part in the discovery and development of drug candidates. However, it requires regular maintenance of cell cultures, and the cell assays can only be performed when the cells have reached 70-80% confluency. READ MORE

  5. 4. Evaluering av graded glucose infusion som metod för utvärdering av β-cellsfunktion hos häst

    University essay from SLU/Dept. of Clinical Sciences

    Author : Linda Nyqvist; [2022]
    Keywords : ekvint metabolt syndrom; GGI; reproducerbarhet; β-cellsfunktion; häst;

    Abstract : Ekvint metabolt syndrom (EMS) kännetecknas av en samling fysiologiska förändringar som bland annat predisponerar hästar för endokrin fång. Centralt i begreppet är insulindysreglering, som beskriver störningar i insulinutsöndringen, så som hyperinsulinemi och insulinresistens. READ MORE

  6. 5. Dose-response for predicting skin sensitization potency with the GARD®skin method

    University essay from Lunds universitet/Institutionen för immunteknologi

    Author : Olivia Eliasson; [2019]
    Keywords : Dose-response; In vitro assay; GARD; skin sensitization; allergic contact dermatitis; chemical sensitizers; hazard assessment; skin sensitization potency; immunotoxicology; Technology and Engineering; Biology and Life Sciences;

    Abstract : Allergic contacts dermatitis is a major health problem in the world and the disease is caused by a type IV hypersensitivity to a small chemical called a hapten. These substances are common in cosmetics, perfumes, pharmaceuticals and house-hold products, and risk factors include both inherent factors and frequent or high exposure. READ MORE