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Showing result 16 - 20 of 265 essays matching the above criteria.

  1. 16. Effect of DNAJB6 on α-synuclein amyloid fibril aggregation and dis-aggregation

    University essay from Lunds universitet/Biofysikalisk kemi

    Author : Josef Getachew; [2023]
    Keywords : α-synuclein; alpha-synuclein; chaperones; DNAJB6; the unhappy chaperone; parkinsons disease; biophysical chemistry; biochemistry; Biology and Life Sciences; Chemistry; Technology and Engineering;

    Abstract : Amyloid proteins are a group of proteins with the ability to form large fibrillar aggregates, identifiable by their cross-β core structure. These aggregates are linked to several different neurodegenerative diseases such as Parkinson’s disease and Alzheimer’s disease and due to the growing rate of people diagnosed, there is a need to combat these diseases. READ MORE

  3. 17. Characterization of potato protein and its calcium binding capacity

    University essay from Lunds universitet/Beräkningskemi; Lunds universitet/Tillämpad biokemi

    Author : Signe König; Erika Thomson; [2023]
    Keywords : Patatin; Calcium; Food supplement; Calcium Assay; Alcalase; potato protein; Applied biochemistry; Biology and Life Sciences; Technology and Engineering;

    Abstract : Calcium is essential for the human body as it has functions in the nervous system, bones and formation of teeth. Deficiency in this important nutrient can be detrimental to health and cause life-long issues. Calcium can be found in various foods, like dairy products, but certain plant-based alternatives to milk needs to be fortified with calcium. READ MORE

  4. 18. Novel tools for high-throughput genetic engineering, selection, and screening for improved Biotin production in E. coli cell factories

    University essay from Lunds universitet/Bioteknik (master); Lunds universitet/Bioteknik (CI)

    Author : Wibke Vellguth; [2023]
    Keywords : biotin; BioB; biotin synthase; oxidative stress; E. coli; biotechnology; Biology and Life Sciences;

    Abstract : Biotin is an essential co-factor in various metabolic processes and is crucial for the growth and maintenance of living organisms. The market need for biotin is multifaceted and driven by its importance in human health, beauty and cosmetics applications, pharmaceuticals, animal nutrition, and other industries. READ MORE

  5. 19. Autophagy and senescence in primary human bronchial epithelial cells in the context of COPD

    University essay from Lunds universitet/Examensarbeten i molekylärbiologi

    Author : Annie Vegraeus; [2023]
    Keywords : Biology and Life Sciences;

    Abstract : Chronic obstructive pulmonary disease (COPD) is the third largest cause of death worldwide, with its most prominent risk factor being inhalation of smoke and pollutants. In this project, we studied two processes that are involved in COPD: autophagy and cellular senescence. READ MORE

  6. 20. Optimization of two high-performance size-exclusion chromatography methods with diode-array detection for protein quantification and purity assessment

    University essay from Lunds universitet/Centrum för analys och syntes

    Author : Camilla Lane; [2023]
    Keywords : Method qualification; Protein concentration; Protein Purity; High Performance Size exclusion chromatography; Quality control; Analytical chemistry; Biology and Life Sciences;

    Abstract : Background: There is a need to develop methods of determining concentration and purity for two new affinity ligands, protein T and protein H, in order to ensure the quality of an industrial production of said proteins. Aims: To develop a High Performance Size Exclusion Chromatography, HPSEC, method to determine concentration and purity of protein T and to improve an existing HPSEC method for concentration and purity determination of protein H that show selectivity, display linearity between peak area and injection amount and give repeatable results. READ MORE