Essays about: "In-Cell BBB-trans assay"
Found 1 essay containing the words In-Cell BBB-trans assay.
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1. Design, production and in vitro evaluation of brain shuttle scFc-scFv8D3 affinity-mutants
University essay from Uppsala universitet/Institutionen för farmaciAbstract : The blood brain barrier (BBB) is a challenge when developing monoclonal antibodies for neurological diseases as antibodies do not cross the BBB making brain distribution challenging. An antibody construct which binds mTfR1 to pass the BBB, scFc-scFv8D3, have previously been developed. READ MORE
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