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  1. 1. Development of siRNA against the CYP1A1 gene for trap of endogenous Ah-receptor ligand

    University essay from Institutionen för livsvetenskaper

    Author : Sara Pettersson; [2006]
    Keywords : The arylhydrocarbon receptor; siRNA;

    Abstract : The aryl hydrocarbon receptor (Ah-receptor) is a member of the bHLH-PAS protein family. The Ah-receptor is a ligand dependent transcription factor, which activates a wide range of genes, most notably the xenobiotica metabolising genes, CYP1A1 and CYP1A2. READ MORE