Essays about: "AF2"

Found 5 essays containing the word AF2.

  1. 1. Design and Evaluation of Peptide Binders : In silico evaluation and comparison of generative AI for de novo peptide binder design

    University essay from Uppsala universitet/Beräkningsbiologi och bioinformatik

    Author : Linde Brokmar; [2023]
    Keywords : Protein design; de novo design; protein engineering; generative ai; machine learning; peptide binders; AF2; EvoBind; RFdiffusion; ProteinMPNN;

    Abstract : Peptide binders are short proteins that bind to larger proteins. Due to peptide binders having high specificity and being cheap to synthesize, they are a prime candidate for drug design. Creating new proteins in silico can be divided into three steps: protein backbone generation, sequence design, and computational filtering. READ MORE

  3. 2. Determining Protein Conformational Ensembles by Combining Machine Learning and SAXS

    University essay from KTH/Tillämpad fysik

    Author : Samuel Eriksson Lidbrink; [2023]
    Keywords : AlphaFold; AlphaFold2; SAXS; protein conformational ensembles; machine learning; protein conformations; reweighting; SAXS; AlphaFold; AlphaFold2; proteinkonformationsensembler; maskininlärning; proteinkonformationer; omviktning;

    Abstract : In structural biology, immense effort has been put into discovering functionally relevant atomic resolution protein structures. Still, most experimental, computational and machine learning-based methods alone struggle to capture all the functionally relevant states of many proteins without very involved and system-specific techniques. READ MORE

  4. 3. A Comparative Study of Electrodes and Membranes for Anion Exchange Membrane Water Electrolysis Systems

    University essay from KTH/Tillämpad elektrokemi

    Author : Parth Omprakash Dayama; [2021]
    Keywords : water electrolysis; membrane; electrocatalysts; anion exchange membrane; hydrogen; vattenelektrolys; membran; elektrokatalysatorer; anjonbytande membran; vätgas;

    Abstract : Vätgas kan framställas från förnybara energikällor genom vattenelektrolys med anjonbytande membran (AEMWE). AEMWE har vissa fördelar jämfört med traditionell alkalisk vattenelektrolys och elektrolysmed protonledande membran. READ MORE

  5. 4. Techno-Economic Analysis of Small-Scale Polygeneration Systems for a Ground Based Air Defence Operations Center in the Swedish Armed Forces

    University essay from KTH/Kraft- och värmeteknologi

    Author : Alma Klipic; Sidar Eken; [2020]
    Keywords : Polygeneration; STandUP;

    Abstract : Climate change is an important topic of today's discussion where scientists have determined that a large proportion of the increasing global temperatures is a product of the increasing greenhouse gases in the atmosphere. Globally it is expected that the share of renewable power generation is set to increase with 50 % between 2019 and 2024. READ MORE

  6. 5. Aqueous Phase Geochemical Characterization and Delineation of Low Arsenic Aquifers in Matlab Upazila, SE Bangladesh.

    University essay from KTH/Miljögeokemi och ekoteknik

    Author : Rajib Hassan Mozumder; [2011]
    Keywords : arsenic; Bangladesh; groundwater; mitigation; color tool; aquifer; highstand; lowstand;

    Abstract : The fact that the former highstand whitish sediments of Plio-Pleistocene and lowstand off-white/red sediments of Late Pleistocene containing low As concentrations in the Bengal basin forms the premise for developing a color tool by the ‘Sustainable Arsenic Mitigation Project’ (SASMIT) to guide the local drillers of Matlab, SE Bangladesh, so that they can target low As aquifers. Groundwater samples collected from the black group of sediments representing a highly reducing environment contains very high concentrations of As, Fe2+ , NH4+, PO43-, HCO3–, and DOC and very low SO42- and Mn2+ concentrations; and vice-versa for the red/offwhite/white group of sediments, thus representing a less reducing condition. READ MORE