Essays about: "Drug information"

Showing result 1 - 5 of 142 essays containing the words Drug information.

  1. 1. Quantification of Pharmaceuticals at the sub-cellular level using the NanoSIMS

    University essay from Uppsala universitet/Analytisk kemi

    Author : Maryam Dost; [2024]
    Keywords : Mass spectroscopy imaging; AstraZeneca; Nanosims; Therapeutics; pharmacokinetics; pharmacodynamics; Quantitative Visualization; calibration curve; RSF; pharmacology; Data Analysis; Chemistry; Quantification; isotopes; Pharmaceuticals; subcellular; drug; drug target; nucleotide; biodistribution; Bioanalytical electrochemistry; spectroscopy; mass spectrometry; analytical separations; Analytical Chemistry; ROI; Bioanalytical Chemistry; Masspektroskopi avbildning; AstraZeneca; Nanosims; Terapeutik; farmakokinetik; farmakodynamik; Kvantitativ visualisering; kalibreringskurva; RSF; farmakologi; Dataanalys; Kemi; Kvantifiering; isotoper; Läkemedel; subcellulär; läkemedel; läkemedelsmål; bioskopisk elektrofördelning; nukleotid; bioskopisk bioskopisk distribution; masspektrometri; analytiska separationer; analytisk kemi; bioanalytisk kemi;

    Abstract : Mass spectroscopy imaging (MSI) has become a vital tool in modern research due to its ability to visualize the spatial distribution of molecules within tissue samples. The collaboration between researchers at AZ, the University of Gothenburg, and Chalmers University of Technology using the NanoSIMS instrument and MSI-SIMS technology has opened up new avenues of exploration in pharmaceutical development, particularly in examining drugs and metabolites at sub-cellular levels. READ MORE

  3. 2. Combining Cell Painting, Gene Expression and Structure-Activity Data for Mechanism of Action Prediction

    University essay from Uppsala universitet/Nationellt resurscentrum för biologi och bioteknik

    Author : Erik Everett Palm; [2023]
    Keywords : bioinformatics; deep learning; machine learning; joint model; tabular data; image data;

    Abstract : The rapid progress in high-throughput omics methods and high-resolution morphological profiling, coupled with the significant advances in machine learning (ML) and deep learning (DL), has opened new avenues for tackling the notoriously difficult problem of predicting the Mechanism of Action (MoA) for a drug of clinical interest. Understanding a drug's MoA can enrich our knowledge of its biological activity, shed light on potential side effects, and serve as a predictor of clinical success. READ MORE

  4. 3. Analyzing the performance of active learning strategies on machine learning problems

    University essay from Uppsala universitet/Avdelningen för systemteknik

    Author : Vendela Werner; [2023]
    Keywords : computer science; bioinformatics; machine learning; active learning; artificial intelligence; supervised learning; Astrazeneca; maskininlärning; artificiell intelligens; datorvetenskap; active learning; bioinformatik; supervised learning;

    Abstract : Digitalisation within industries is rapidly advancing and data possibilities are growing daily. Machine learning models need a large amount of data that are well-annotated for good performance. To get well-annotated data, an expert is needed, which is expensive, and the annotation itself could be very time-consuming. READ MORE

  5. 4. Screening of HETP test conditions and resin storage solutions for HIC

    University essay from Uppsala universitet/Analytisk farmaceutisk kemi

    Author : Lise-Lotte Ronnerfors; [2023]
    Keywords : Hydrophobic Interaction Chromatography; Pfizer Health AB; Column packing;

    Abstract : Hydrophobic interaction chromatography (HIC) is a common purification method for biological drug substances. For continuous monitoring the quality of the purification, a column performance test is carried out to test the packing of the resin. READ MORE

  6. 5. Advancements of 3D Bioprinting : A market development study

    University essay from Uppsala universitet/Institutionen för samhällsbyggnad och industriell teknik

    Author : Alexander Brandt; [2023]
    Keywords : 3D bioprinting; Market; market developmet; Technology readiness levels;

    Abstract : In most cases new technology emergence does not guarantee overnight success nor is it developed overnight, rather it is a result of industry expertise spanning over several fields of research. 3D bioprinting is an industry that promises revolutionary implications for healthcare and scholars are discussing application areas such as tissue for oncology research, tissue for patient specific drug development and lastly complex organs for implantation. READ MORE