Essays about: "IgG Subclass"
Found 4 essays containing the words IgG Subclass.
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1. Selection of a calcium-dependent IgG1-binding protein domain
University essay from Uppsala universitet/Institutionen för biologisk grundutbildningAbstract : Standard purification processes in large scale antibody production are largely dependent on Protein A chromatography. Protein A binds specifically to many subclasses of IgG with high affinity. However, in order to elute the proteins, the pH needs to be lowered. READ MORE
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2. Development of an Antigen-independent Affinity Assay to study the Binding of IgG to FcgammaR
University essay from Lunds universitet/Kemiska institutionenAbstract : Fc gamma receptors (FcγRs) are membrane-bound receptors which bind the Fc fragment of antigen-bound IgGs. The binding generates cell signaling and subsequently an immunological response. In this way FcγRs are important links between the humoral and cellular parts of the immune system. READ MORE
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3. New SPR based assays for plasma protein titer determination
University essay from Institutionen för fysik, kemi och biologiAbstract : Reliable analytical tools are important for time efficient and economical process development, production and batch release of pharmaceuticals. Therapeutics recovered from human plasma, called plasma protein products, involve a large pharmaceutical industry of plasma fractionation. READ MORE
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4. Affinity Determination of Protein A Domains to IgG subclasses by Surface Plasmon Resonance
University essay from Institutionen för fysik, kemi och biologiAbstract : A capture step with protein A is the most common purification step in the downstream purification process of monoclonal antibodies. It is therefore of great importance to increase the knowledge of the interactions involved in this purification technique. READ MORE
