Essays about: "herpes simplex virus"

Found 5 essays containing the words herpes simplex virus.

1. 1. The future of viral vectors for gene therapy

   University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

   Author : Elias Ekstedt; Inna Fryckstedt; Hanna Hyllander; Josefin Jonsson; Elin Ring; Felix Wærn; [2021]
   Keywords : Gene therapy; adenovirus; alpharetrovirus; baculovirus; adeno-associated virus; lentivirus; herpes simplex virus; foamy virus; gammaretrovirus;

   Abstract : Gene therapy is a fast growing technology that offers treatments for genetic diseases. The method is based on introducing genetic material into a patient to replace the disease-causing gene, using a vector. READ MORE

3. 2. Exploration of Zinc finger CCCH domain-containing protein 11A’s role in mammalian cell NFkB Pathway

   University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

   Author : Jianxiang Wang; [2019]
   Keywords : ZC3H11A; NFkB; HeLa cells; Viral-host interaction;

   Abstract : ZC3H11A (ZC3) protein has been reported to be part of the TREX (TRanscription-EXport) nuclear export system for mammalian cells. According to our previous publication, ZC3 not only plays an unelucidated role in the TREX complex, but also supports the growth of several human nucleus replicating virus, such as influenza virus, adenovirus (HAdV), herpes simplex virus and HIV. READ MORE

4. 3. A Versatile Group of Molecules, Can Defensins Make an Impact in Medicine?

   University essay from Linköpings universitet/Institutionen för fysik, kemi och biologi

   Author : Filip Fors; [2019]
   Keywords : Defensin Therapy Biomarker Antiviral Wound Treatment;

   Abstract : Antimicrobial peptides are an ancient form of innate defense and is present in all ways of life. In humans they are present as cathelicidins and defensins. Both are important for the immune system and they exhibit activity against viruses, bacteria and fungi. READ MORE

5. 4. Effects of herpes simplex virus 1 (HSV-1) infection on nuclear amyloid aggregation

   University essay from KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

   Author : Maria Arone Blanco; [2018]
   Keywords : Huntington’s disease; Spinocerebellar ataxia; Amyloids; Protein aggregation; Herpes Simplex Virus 1; HSV-1; Virus infection; oligonucleotides; Filter retardation Assay; Dot Blot.; Huntingtons sjukdom; Spinocerebellära ataxier; Amyloider; Protein aggregering; Herpes Simplex Virus 1; HSV-1; Virus infektion; Oligonukleotider; Filter retardation Assay; Dot Blot.;

   Abstract : Huntington’s disease (HD) and Spinocerebellar ataxia (SCA) are incurable neurodegenerative diseases that affect the central nervous system. Amyloids, highly organized protein aggregates, are a hallmark for many neurodegenerative diseases. The presence and accumulation of amyloids are toxic and constitute the major cause of neuron cell death. READ MORE

6. 5. Cloning, Expression and Purification of a Mutant Tomato Thymidine Kinase 1 for Crystallography

   University essay from Lunds universitet/Tillämpad biokemi

   Author : Mohamad Nesrini; [2015]
   Keywords : protein expression; protein engineering; Azidothymidine; thymidine kinase; deoxyribonucleoside kinases; nucleosides; nucleoside analog; suicide gene therapy; tillämpad biokemi; applied biochemistry; BEVS.; Technology and Engineering; Chemistry;

   Abstract : Thymidine kinase 1 from tomato (ToTK1) is a newly discovered deoxyribonucleoside kinase (dNK) that has been subject to study due to its in vitro and in vivo properties making it an interesting suicide gene candidate for the treatment of brain tumors. The ToTK1 phosphorylates the nucleoside analogue 3-azido-2,3-dideoxythymidine (azidothymidine, AZT) equally well as its natural substrate thymidine (dThd). READ MORE