Essays about: "p53"

Showing result 1 - 5 of 21 essays containing the word p53.

  1. 1. Targeting the epigenetic state of refractory and relapsing acute myeloid leukaemia

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Ojong Tabi Ojong Besong; [2021]
    Keywords : ;

    Abstract : Acute myeloid leukaemia (AML) is a heterogeneous group of myeloid lineage malignancies arising from a spectrum of mutations. AML is characterized by the uncontrolled proliferation of clonal cells, which are unable to properly differentiate into mature myeloid cells. READ MORE

  3. 2. The circadian rhythm of the cells is dependent of the pH of the cell

    University essay from Högskolan i Skövde/Institutionen för hälsovetenskaper

    Author : Maria Ines Berrojo Romeyro Mascarenhas; [2020]
    Keywords : ;

    Abstract : Circadian rhythms are endogenic autonomous oscillators of physiological activities resulting from 24-hour day/night cycles. Circadian rhythms regulate a wide variety of metabolic and physiological functions. This allows the organism to control its molecular, biochemical, physiological, and behavioural processes. READ MORE

  4. 3. Investigation of drug-induced cell cycle responses in high-risk neuroblastoma

    University essay from KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Author : Maryam Sahi; [2020]
    Keywords : Neuroblastoma; chemotherapy resistance; cell cycle arrest; cisplatin; doxorubicin; ATM; Chk1; Wee1; Neuroblastom; kemoterapiresistans; cellcykelarrest; cisplatin; doxorubicin; ATM; Chk1; Wee1;

    Abstract : The childhood cancer neuroblastoma mostly affects children under the age of 2 and comprises 6% of all childhood cancers. Neuroblastoma has very diverse phenotypes caused by both inter- and intra-tumour heterogeneities. The phenotypes are classified as being either low- or high-risk. READ MORE

  5. 4. Mapping the Expression of Cyclin Dependent Kinase Inhibitors in High-Risk Neuroblastoma Cell Lines : Dynamics on Cell-Fate Decisions on Proliferation/Cell Cycle Arrest

    University essay from KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Author : Ximena López Lorenzo; [2020]
    Keywords : Neuroblastoma; NMYC; p53; cell cycle checkpoint; inhibition; regrowth; p21; p27; SKP2; CHK1 2; Neuroblastoma; NMYC; p53; cellcykel checkpoint; hämning; återväxt; p21; p27; SKP2; CHK1 2;

    Abstract : Poor prognosis for high-risk neuroblastoma patients makes it necessary to find novel treatmentstrategies. This work aims to understand the cell cycle behavior of various high-riskneuroblastoma cell lines following chemotherapy treatment. READ MORE

  6. 5. Evaluation of peptide-receptor radionuclide therapy in breast cancer and neuroblastoma, in combination with the radio-sensitizing drug VIP-116

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Bonoshree Dey; [2018]
    Keywords : ;

    Abstract : Cancer being one of the leading causes of death globally, raises an international fight to defeat and finally conquer cancer. It represents more than 200 different diseases that individually have varying symptoms and treatments. The p53-pathway is of great interest as it has shown to be crucial in the formation of cancerous cells. READ MORE