Essays about: "tumor-associated macrophages"

Showing result 1 - 5 of 6 essays containing the words tumor-associated macrophages.

  1. 1. Investigating the crosstalk between estrogen receptor beta in colorectal cancer and tumor-associated macrophages

    University essay from KTH/Proteinvetenskap

    Author : Alicia Bodin; [2023]
    Keywords : estrogen; macrophages; colorectal cancer; qPCR; cell culture; östrogen; makrofager; tjocktarmscancer; qPCR; cellodling;

    Abstract : Tjock-och ändtarmscancer (kolorektalcancer) är den tredje vanligaste cancertypen och den näst vanligaste cancer-relaterade dödsorsaken i världen. Östrogen har visat sig ha en skyddande roll mot kolorektalcancer och östrogenreceptor beta är den dominerande östrogenreceptorn i normalt kolonepitel. READ MORE

  3. 2. Digital Image Analysis using Qupath to determine immune cell content in formalin-fixed, paraffin-embedded murine neuroblastoma tumors

    University essay from Uppsala universitet/Institutionen för farmaceutisk biovetenskap

    Author : Anton Bergström Holm; [2023]
    Keywords : Neuroblastoma; Tumor-associated neutrophils TANs ; Digital image analysis; QuPath;

    Abstract : Neuroblastoma (NB), an extracranical solid tumor, is among the most prevalent cancers affecting children, particularly those under the age of five. High-risk NB presents a survival rate just below 50 %. Angiogenesis, a crucial process in NB, is induced by various pro-angiogenic factors. READ MORE

  4. 3. The effect of deactivation or silencing of tumor stroma with angiogenesis inhibitor on malignancy of tumor metastases

    University essay from Uppsala universitet/Institutionen för farmaceutisk biovetenskap

    Author : Nataly Tachijian; [2021]
    Keywords : neuroblastoma; SU11248; angiogenesis; tumor-associated macrophages; immunohistochemistry;

    Abstract : Background: Neuroblastoma (NB) is a pediatric tumor in infants and young children. The survival rate is only around 50 percent for high-risk NB despite advanced and intense multi-modal therapy. Current research aims to find new effective treatment additional to modern therapy to improve prognosis of high-risk NB in children. READ MORE

  5. 4. Tumör-associerade makrofagers inverkan vid juvertumörer hos hund

    University essay from SLU/Dept. of Biomedical Sciences and Veterinary Public Health

    Author : Martin Kläschen; [2019]
    Keywords : tumör-associerade makrofager; TAM; makrofager; juvertumör; CMT; hund;

    Abstract : Tumör-associerade makrofager (TAM) är makrofager som under påverkan av tumörceller polariseras mot ett stadie där de frisätter tillväxtfaktorer, cytokiner, kemokiner och enzymer som främjar tumörtillväxt, kärlnybildning, invasion och metastasering. Det har konstaterats att ett högre antal TAM i juvervävnad på hund är associerat med en sämre prognos jämfört med hundar med ett lägre antal TAM. READ MORE

  6. 5. The role of CSF-1R on migration and invasion of canine mammary tumors

    University essay from SLU/Dept. of Anatomy, Physiology and Biochemistry

    Author : Johanna Bager Björzén; [2017]
    Keywords : CSF-1R; M-CSFR; colony stimulating factor-1; macrophage colony stimulating factor; mammary tumor; mammary cancer; canine; kolonistimulerande faktor-1; makrofag kolonistimulerande faktor; juvertumör; juvercancer; hund;

    Abstract : The colony stimulating factor-1 receptor (CSF-1R) is a tyrosine kinase receptor expressed in mammary tumors of canines and breast carcinomas of humans. The expression of this receptor has been associated with increased invasion and migration in vitro. READ MORE