Essays about: "Affinity chromatography"

Showing result 1 - 5 of 62 essays containing the words Affinity chromatography.

1. 1. Detecting Chromatography Unit Degradation : Comparison of single- and multi-point techniques implemented in system control and monitoring software

   University essay from Uppsala universitet/Signaler och system

   Author : Max Markensten; [2023]
   Keywords : PCA; SOP-MPT; Fibro; chromatography; affinity A;

   Abstract : Chromatography units, used in the production of pharmaceuticals, degrade with use and need to be changed or repackaged. This study investigates the effectiveness of two statistical methods, principal component analysis and simple and one-point multiparameter technique, for determining degradation in the Fibro chromatography unit. READ MORE

3. 2. Characterization of Mitilysin Pores by Cryo-electron Microscopy

   University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

   Author : Vladimir Novakovic; [2023]
   Keywords : Mitilysin; Mly; Structural Biology; Cryo-EM; pore; toxin; pore forming proteins; pore forming toxins; PFP; PFT;

   Abstract : Pore forming toxins (PFTs) are a large group of proteins found mainly in bacteria with some exceptions found in animals. They bind and form pores in their target membranes and form pores, which leads to cell death. Among these are cholesterol-dependent cytolysins (CDC), which require the presence of cholesterol to bind target membranes. READ MORE

4. 3. A novel approach for functionalising and separating Tröger's Base Analogues

   University essay from Lunds universitet/Centrum för analys och syntes

   Author : Emil Jakobsson; [2023]
   Keywords : Tröger s Base; Synthesis; Chromatography; Supramolecular chemistry; Diastereomers; Organic chemistry; Chemistry;

   Abstract : Tröger’s Base (TB) is a bicyclic compound containing a methanodiazocine group between two aromatic rings. The methylene bridge forces the molecule to have a bent formation; thus, the aromatic rings are close to 90 degrees relative to each other, resulting in a rigid concave aromatic cavity. READ MORE

5. 4. Design, production and in vitro evaluation of brain shuttle scFc-scFv8D3 affinity-mutants

   University essay from Uppsala universitet/Institutionen för farmaci

   Author : Jonathan Efverström; [2023]
   Keywords : Blood-brain barrier; In-Cell BBB-trans assay; mTfR1; Transferrin receptor; scFc-scFv8D3; Blod-hjärn barriären; mTfR1; Transferrin receptorn; scFc-scFv8D3;

   Abstract : The blood brain barrier (BBB) is a challenge when developing monoclonal antibodies for neurological diseases as antibodies do not cross the BBB making brain distribution challenging. An antibody construct which binds mTfR1 to pass the BBB, scFc-scFv8D3, have previously been developed. READ MORE

6. 5. Characterization of potato protein and its calcium binding capacity

   University essay from Lunds universitet/Beräkningskemi; Lunds universitet/Tillämpad biokemi

   Author : Signe König; Erika Thomson; [2023]
   Keywords : Patatin; Calcium; Food supplement; Calcium Assay; Alcalase; potato protein; Applied biochemistry; Biology and Life Sciences; Technology and Engineering;

   Abstract : Calcium is essential for the human body as it has functions in the nervous system, bones and formation of teeth. Deficiency in this important nutrient can be detrimental to health and cause life-long issues. Calcium can be found in various foods, like dairy products, but certain plant-based alternatives to milk needs to be fortified with calcium. READ MORE