Essays about: "Candidate Drug"
Showing result 1 - 5 of 27 essays containing the words Candidate Drug.
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1. Design and Evaluation of Peptide Binders : In silico evaluation and comparison of generative AI for de novo peptide binder design
University essay from Uppsala universitet/Beräkningsbiologi och bioinformatikAbstract : Peptide binders are short proteins that bind to larger proteins. Due to peptide binders having high specificity and being cheap to synthesize, they are a prime candidate for drug design. Creating new proteins in silico can be divided into three steps: protein backbone generation, sequence design, and computational filtering. READ MORE
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2. A novel approach for functionalising and separating Tröger's Base Analogues
University essay from Lunds universitet/Centrum för analys och syntesAbstract : Tröger’s Base (TB) is a bicyclic compound containing a methanodiazocine group between two aromatic rings. The methylene bridge forces the molecule to have a bent formation; thus, the aromatic rings are close to 90 degrees relative to each other, resulting in a rigid concave aromatic cavity. READ MORE
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3. Predicting Biomarkers/ Candidate Genes involved in iALL, using Rough Sets based Interpretable Machine Learning Model.
University essay from Uppsala universitet/Institutionen för biologisk grundutbildningAbstract : Acute lymphoblastic leukemia is a hematological malignancy that gains a proliferative advantage and originates in the bone marrow. One of the more common genetic alterations in ALL is KMT2A-rearrangement which constitutes 80% of the cases of ALL in infants. READ MORE
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4. Information and communications technology support for medication review in nursing home residents : Update of the OptiMEDs tool and an evaluation of the improvement of the new version
University essay from Uppsala universitet/Institutionen för farmaciAbstract : Background: In older age polypharmacy is common due to a higher rate of chronic diseases. Taking multiple medications can result in drug related problems resulting in higher health care costs. READ MORE
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5. Benchmarking Machine Learning Methods for Peptide Activity Predictions
University essay from Göteborgs universitet/Institutionen för data- och informationsteknikAbstract : One of the main challenges in the drug discovery process is to find a suitable compound for further analysis. The compound must affect the target relevant for the specific disease, while at the same time have desired properties to make it a safe and efficient drug candidate. READ MORE