Essays about: "Acute Lymphoblastic Leukemia"

Showing result 1 - 5 of 6 essays containing the words Acute Lymphoblastic Leukemia.

  1. 1. Predicting Biomarkers/ Candidate Genes involved in iALL, using Rough Sets based Interpretable Machine Learning Model.

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Girish Pulinkala; [2023]
    Keywords : Machine Learning; Cancer; Oncology; Acute Lymphoblastic Leukemia; Rough sets; Pathway analysis; Feature selection; Bioinformatics; Computational Biology.;

    Abstract : Acute lymphoblastic leukemia is a hematological malignancy that gains a proliferative advantage and originates in the bone marrow. One of the more common genetic alterations in ALL is KMT2A-rearrangement which constitutes 80% of the cases of ALL in infants. READ MORE

  3. 2. Investigation of DNA Base Excision Repair in MTH1 Depleted T-cell Acute Lymphoblastic Leukemia cells

    University essay from KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Author : Zahra Mavajian; [2018]
    Keywords : Oxidative stresses; DNA repair; 8-oxo-dG; T cell ALL; MTH1; MUTYH.;

    Abstract : Genomic alterations may initiate cancer development as the consequence of endogenous or exogenous DNA damaging factors. Defects in DNA repair mechanisms may also facilitate cancer progression as well as accumulation of mutations which favor cancer cell survival. READ MORE

  4. 3. Classifying Microscopic Images for Acute Lymphoblastic Leukemia (ALL) using Bayesian Convolutional Neural Networks

    University essay from Örebro universitet/Handelshögskolan vid Örebro Universitet

    Author : Mohammad Ehtasham Billah; [2018]
    Keywords : ;

    Abstract : .... READ MORE

  5. 4. Interaction Design - by the protocol : Combining user-centered design methods for finding user needs in a time-­‐constrained environment

    University essay from KTH/Skolan för datavetenskap och kommunikation (CSC); KTH/Skolan för teknikvetenskaplig kommunikation och lärande (ECE)

    Author : Christoffer Svanberg; Anton Westman; [2015]
    Keywords : User-­‐centered design; usability; participatory design; time-­‐constrained users; evaluation methods; health care; interaction design; prototyping; iterative design; human-­‐computer interaction.;

    Abstract : ABSTRACT Today there are lots of different health care computer systems in use. However, according to recent studies many of them lack necessary usability. Within Nordic pediatric cancer care, analogue treatment protocols on paper are currently used, as a complement to the digital medical records and prescription systems. READ MORE

  6. 5. In vitro studies of Thiopurine S-Methyltransferase: Ligand binding interactions and development of a new enzymatic activity assay for TPMTwt, TPMT*6 and TPMT*8

    University essay from Linköpings universitet/Institutionen för fysik, kemi och biologi; Linköpings universitet/Tekniska fakulteten

    Author : Lovisa Hemmingsson; Johan Klasén; [2015]
    Keywords : Thiopurine S-Methyltransferase; 6-mercaptourine; methotrexate; isothermal titration calorimetry; fluorescence spectroscopy;

    Abstract : Acute lymphoblastic leukemia, one of the most malignant cancer forms in children is commonly treated with the thiopurine 6-mercaptopurine (6-MP) in combination with a high dose of methotrexate (MTX). 6-Mercaptopurine is in the body metabolized by the enzyme thiopurine S-methyltransferase (TPMT). READ MORE